Publications by authors named "Yujian Niu"
Objective: To provide a disease-specific instrument for evaluating the health-related quality life of Chinese kidney allograft recipients.
Methods: Cross-cultural adaptation of the Kidney Transplant Questionnaire (KTQ) was performed by forward translation of the original English version into Chinese, followed by back translation and evaluation of the Chinese version by health care professionals, language professionals, and the translators.
Results: A total of 297 patients (110 women and 187 men; mean age, 43.
Objectives: Our objective was to explore factors influencing health-related quality of life in living-donor kidney transplant recipients.
Materials And Methods: A total of 140 kidney transplant recipients, enrolled between December 2014 and April 2015, were administered questionnaires on medical outcomes, 36-item Short Form Health Survey, medical coping modes, cognitive appraisal of health scale, and adverse effects of medications. Path analysis was employed to verify the hypothesized model.
Objective: To explore the feasibility of the Chinese version of Kidney Transplant Questionnaire (KTQ) by evaluating the health-related quality of life (HRQoL) in Chinese recipients of living donor kidney transplantation.
Methods: The English version of KTQ was translated into Chinese and underwent cultural adaptation to obtain the Chinese version of KTQ. HRQoL of 136 Chinese recipients of living donor kidney transplantation that met the inclusion criteria were evaluated to assess the validity and reliability of the questionnaire.
Parents of liver transplant recipient children have to face complicated health issues of their children. Coping strategies of parents as major care providers not only impacts on their handling of stresses on themselves but also on the recipients' quality of life. In this study, we sought to investigate the coping strategies of parents of Chinese pediatric liver transplant recipients at a single tertiary care institution in China.
View Article and Find Full Text PDFAnti-HBc-positive/HBsAg-negative liver donors pose a higher risk of occult HBV infection but do not cause severe histological damage in liver grafts.
Clin Res Hepatol Gastroenterol
September 2014
Background: The use of serum anti-hepatitis B core antibody (HBc)-positive/hepatitis B surface antigen (HBsAg)-negative liver donors for patients with hepatitis B virus (HBV)-related liver disease (HBRLD) is a promising means of expanding the organ donor pool and does not increase the risk of HBV recurrence. However, whether such donors will compromise the histology of the liver grafts is unclear.
Methods: Among 84 patients who underwent transplantation for HBRLD and who did not have post-transplant HBV recurrence (non-detectable serum HBsAg and HBV DNA), 19 underwent liver biopsy (eight received anti-HBc-positive/HBsAg-negative liver grafts; 11 received anti-HBc-negative liver grafts) and were included in the study.
Objective: To investigate the diabetogenic effects of the immunosuppressive agent tacrolimus, the reversibility of these effects upon treatment discontinuation, and the underlying mechanisms in a rat model.
Materials And Methods: 60 healthy male rats were randomly divided into three groups for intragastric administration of tacrolimus either at 4 mg/kg/d or 2 mg/kg/d or an equal volume of normal saline (control). The treatment was administered for 5 months, followed by a 5-month period of no intervention.
Vasculitis of anti-neutrophil cytoplasmic antibody after liver transplantation.
J Craniofac Surg
January 2014
Objective: We reported a case of vasculitis of anti-neutrophil cytoplasmic antibody after liver transplantation. A 56-year-old male patient underwent orthotopic liver transplantation of the classic style on February 25, 2010 because of alcoholic cirrhosis.
Methods: Pathology analysis showed it was nodular cirrhosis.
Background: A precise predictive survival model of liver transplantation (LT) with antiviral prophylaxis for hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) and cirrhosis has not been established. The aim of our study was to identify predictors of outcome after LT in these patients based on tumor staging systems, antitumor therapy pre-LT, and antiviral prophylaxis in patients considered to be unfit by Milan or UCSF criteria.
Methods: From 2002 to 2008, 917 LTs with antiviral prophylaxis were performed on patients with HBV-cirrhosis, and 313 had concurrent HCC.
Aim: To compare the immunogenicity of two modified hepatitis B virus (HBV) vaccination schedules in liver transplant recipients. Hepatitis B immunoglobulin (HBIG) in combination with nucleoside/nucleotide analogs (NUCs) is the recommended prophylaxis for preventing HBV recurrence following liver transplantation (LT). However, HBIG treatment is expensive.
View Article and Find Full Text PDF[Causes and therapeutic principles of pulmonary infections in renal transplant recipients].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
June 2009
Article Synopsis
- Pulmonary infections are common complications after kidney transplants, occurring both early and late in the recovery process.
- The causes and implications of these infections are not fully understood, and they can be very serious for some patients.
- Early detection and treatment are crucial, along with reducing immunosuppressant dosages and focusing on preventative care.
Objective: To evaluate the efficacy and safety of hepatitis B immunoglobulin (HBIG) by different medicating ways in patients with liver transplantation and to explore the methods for calculating the intravenous loading dosage of HBIG.
Methods: The patients enrolled were randomized into three groups (i.v group, i.
[Liver transplantation for the treatment of hepatocellular carcinoma].
Zhonghua Zhong Liu Za Zhi
August 2006
Objective: To retrospectively evaluate the clinical outcomes of liver transplantation for patients with hepatocellular carcinoma (HCC).
Methods: The clinical data of 88 consecutive HCC patients who underwent orthotopic liver transplantation between 2002. 4 and 2004.
[Assay of carnitine in plasma and urine of healthy adults].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2002
Article Synopsis
- The study aimed to measure carnitine levels in plasma and urine of healthy adults to establish reference standards for future research on patients.
- High-performance liquid chromatography (HPLC) was used to analyze carnitine levels in 40 adults, revealing significant differences between men and women in both plasma and urinary carnitine concentrations.
- Results showed that higher carnitine levels and daily excretion rates were positively correlated with lean body mass, suggesting that body composition influences carnitine metabolism.