Recently, more than 200 live births following ovarian tissue cryopreservation (OTC) and transplantation in cancer survivors have been reported worldwide. However, cancer survivors with minimal residual disease (MRD) in cryopreserved ovarian tissue are at the risk of relapse through the graft. Here, we report a rare case of a 19-year-old female patient with non-Hodgkin lymphoma who had MRD in the ovary harvested for OTC.
View Article and Find Full Text PDFNKp46 is a natural cytotoxicity receptor expressed by NK cells and its expression is decreased in reproductive failure patients. NKp46 can be subdivided into NKp46 and NKp46 according to different fluorescence staining intensities. We investigated the role of the NKp46 receptor in determining the reproductive outcomes.
View Article and Find Full Text PDFInsights gained from chronological ultrasonogram images in the current case report will provide useful information for diagnosing and conservatively treating HOC. This could help avoid unnecessary laparotomy.
View Article and Find Full Text PDFEndometriosis is a chronic disease that commonly affects women in their reproductive age. It has been reported that the infertility due to endometriosis is largely caused by pelvic adhesion, oocyte damage, and so on. There are several causes of endometriosis including bacterial infections, immunological abnormalities, epigenetics, and aberrant DNA methylation.
View Article and Find Full Text PDFThe high toxicity of chemotherapy can damage a patient's gonadal function, leading to premature ovarian insufficiency (POI). Here, we report the case of a patient suffering from POI after chemotherapy for breast cancer, who 3 years later ovulated spontaneously and became pregnant. The patient, a 31-year-old infertile women, nulligravida, was diagnosed with breast cancer.
View Article and Find Full Text PDFPurpose: Sperm cryopreservation is the gold standard for maintaining fertility in male survivors of cancer. In order to help increase the future success of fertility preservation in these patients, the present state of sperm cryopreservation was examined at the current institution and its challenges were discussed.
Methods: Between January, 2004 and February, 2017, 31 male patients with cancer were introduced to the center for fertility preservation.
•Glassy cell carcinoma (GCC) of the cervix is rare and aggressive.•A few case reports have described a response to intravenous chemotherapy for this malignancy.•This is the first report of a GCC case that responded to a combination of docetaxel and carboplatin.
View Article and Find Full Text PDFGynecol Oncol Case Rep
December 2013
•Multiple bone metastases following cervical cancer was completed resolved.•Metastatic lesions were present within a previously irradiated zone of primary external radiation.•Concurrent chemotherapy and bisphosphonate administration is promising.
View Article and Find Full Text PDF