Spinal anesthesia increases the risk of venous thromboembolism in total arthroplasty: Secondary analysis of a J-PSVT cohort study on anesthesia.

Clinical guidance on the choice of anesthetic modality vis-à-vis the risk of perioperative venous thromboembolism (VTE) is largely lacking because of a paucity of recent evidence. A comparative effect of general anesthesia and neuraxial blockade on the perioperative incidence of VTE has not been well-investigated.We compared the effects of different types of anesthetic modalities on the risk of VTE after total hip arthroplasty (THA) and total knee arthroplasty (TKA).

Venous thromboembolism after total joint arthroplasty: results from a Japanese multicenter cohort study.

Introduction: Real-world evidence of the effectiveness of pharmacological thromboprophylaxis for venous thromboembolism (VTE) is limited. Our objective was to assess the effectiveness and safety of thromboprophylactic regimens in Japanese patients undergoing joint replacement in a real-world setting.

Method: Overall, 1,294 patients (1,073 females and 221 males) who underwent total knee arthroplasty (TKA) and 868 patients (740 females and 128 males) who underwent total hip arthroplasty (THA) in 34 Japanese national hospital organization (NHO) hospitals were enrolled.

Salacia reticulata has therapeutic effects on obesity.

Salacia reticulata Wight (S. reticulata) is a herbal medicine used for treatment of early diabetes in Ayurvedic medicine. In previous reports, the extract of S.

Isomer-selective infrared spectroscopy of the cationic trimethylamine dimer to reveal its charge sharing and enhanced acidity of the methyl groups.

Infrared predissociation spectroscopy of the trimethylamine dimer cation generated by the vacuum-ultraviolet photoionization is isomer-selectively carried out by monitoring two main fragment channels, protonated trimethylamine and the trimethylamine monomer cation. The spectral carriers monitored by these two channels are assigned to different isomers of the trimethylamine dimer cation. One is the charge-shared (hemibond) structure, in which the positive charge is intermolecularly delocalized over the dimer through the interaction between the nonbonding orbitals of the nitrogen atoms.