Publications by authors named "Yuichi Momose"
Article Synopsis
- The study investigates predictors of an acceptable capture threshold for the Micra transcatheter pacing system (Micra TPS) prior to its deployment in patients.
- Researchers assessed the angles of the catheter's gooseneck appearance and the orientation of the device cup using fluoroscopic imaging, finding that specific angles were associated with successful implantation.
- Results indicated that a deflection angle of ≥6° and an elevation angle of ≤30° were key predictors for achieving a low capture threshold, emphasizing the importance of evaluating catheter shape from multiple views before deployment.
Article Synopsis
- Esophageal injury is a rare but serious risk during atrial fibrillation (AF) ablation, and a specific protocol involving complete isolation of the left atrial posterior wall and pulmonary veins was implemented to minimize this risk.
- A study evaluated 105 patients undergoing this ablation approach, finding that 72% were free of arrhythmia after an average follow-up of about 22 months.
- Results showed significant reductions in left atrial size and volume six months post-ablation, even in patients with recurrent AF, indicating that extensive isolation can safely lead to heart remodeling without esophageal complications.
Objectives: This study investigates the effect of stellate ganglion (SG) phototherapy in healthy participants and assesses its efficacy in suppressing electrical storm (ES) refractory to antiarrhythmic drugs and catheter ablation.
Background: Modulation of the autonomic nervous system has been shown to be an effective adjunctive therapy for ES.
Methods: Ten-minute SG phototherapy was performed twice weekly for 4 weeks in 20 healthy volunteers.
Article Synopsis
- * Of the 18 patients who developed PE, the majority were older adults (median age 71), with atrial fibrillation as the most common target arrhythmia (72%).
- * SEventeen patients needed pericardiocentesis to drain fluid, with some experiencing severe complications, including emergency surgeries and one death, indicating significant risks associated with this procedure.
Article Synopsis
- - The study examined how distal His bundle pacing (HBP) from the right ventricle compares to proximal HBP from the right atrium, focusing on their effects on pacing and sensing parameters in patients with bradycardia.
- - Fifty patients were tracked for one year after successful HBP, revealing both types of pacing had similar thresholds, but distal HBP had lower local ventricular thresholds, with 78% of patients maintaining an optimal pacing threshold at 6 months.
- - Atrial oversensing was more common in proximal HBP, and key findings indicate that understanding individual anatomy and heart properties at implantation is essential for sustaining effective pacing and avoiding lead issues.
Objective: Recently, concern has increased regarding the hazards of radiation exposure in patients and laboratory staff. Since the numbers of complex catheter ablations (CA) performed, duration of procedure times, and need for multiple sessions have increased, radiation exposure during each session needs to be minimised. Our study aimed to assess the impact of awareness on radiation exposure during CA for atrial fibrillation (AF).
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- His-bundle pacing (HBP) is a physiological pacing method, and this study investigated predictors of low HBP thresholds in patients, particularly those with bradycardia and some with atrioventricular block.
- In a study involving 51 patients, researchers identified that a deep negative deflection of ≥0.060 mV in His-bundle electrograms (HB EGMs) is significantly associated with achieving an acceptable HBP threshold of ≤2.5 V.
- Follow-up showed that the deep negative HB EGM group maintained lower HBP thresholds compared to the positive EGM group, indicating that analyzing these electrograms after lead fixation could help predict permanent HBP thresholds.
Article Synopsis
- A novel catheter visualization system, known as NFCV, allows for real-time tracking of catheters during procedures using non-fluoroscopic methods, aimed at improving ablation for idiopathic premature ventricular contractions and ventricular tachycardia (i-PVC/VT).
- A study of 30 i-PVC/VT ablation procedures using the NFCV system found that it was effective, with an 87% success rate in eliminating these conditions, comparable to an 84% success rate with traditional fluoroscopy.
- The NFCV system significantly reduced total fluoroscopy time (3.3 minutes vs. 16.6 minutes) and demonstrated safety, as no major complications were reported in its use, unlike one incident of
Article Synopsis
- The study examines the challenges of catheter ablation for atrioventricular nodal reentrant tachycardia (AVNRT), particularly the risk of causing AV block due to close proximity between the His recording site and the coronary sinus ostium (TOK).
- Researchers evaluated various anatomical parameters, including aortic dimensions and echocardiogram results, in 28 patients to predict small TOK during the ablation procedure.
- Findings revealed that aortic unfolding was the only significant predictor of smaller TOK, while longer aortic lengths and larger left ventricular dimensions were also associated with the size of TOK.
Background: There are no criteria for selecting single- or dual-chamber implantable cardioverter defibrillators (ICDs) in patients without a pacing indication. Recent reports showed no benefit of the dual-chamber system despite its preference in the United States. As data on ICD selection and respective outcomes in Japanese patients are scarce, we investigated trends regarding single- and dual-chamber ICD usage in Japan.
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- Plasma amino acid concentrations show unique patterns in various diseases, but the specific patterns in pulmonary hypertension (PH) have not been thoroughly studied.
- Researchers analyzed fasting plasma aminograms from 140 PH patients and found significant differences in amino acid levels when compared to healthy individuals.
- The Fischer ratio, which compares branched-chain to aromatic amino acids, was found to be negatively correlated with clinical severity markers, suggesting that a lower Fischer ratio indicates worse outcomes in PH patients.
A substantial proportion of patients with pulmonary arterial hypertension (PAH) have mutations in the Bone Morphogenetic Protein Receptor type-2 (BMPR2) gene. PAH due to BMPR2 mutations is inherited as an autosomal dominant trait with several unique features, including a wide variety of mutations, reduced penetrance, a skewed gender ratio, variable expressivity and genetic anticipation. To address the genetic background of these unique features of BMPR2 mutation, we conducted a systematic analysis of 15 PAH families with BMPR2 mutation.
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- - The study identified genetic rearrangements in the BMPR2 gene associated with pulmonary arterial hypertension (PAH), specifically through the deletion or duplication of its exons.
- - Researchers examined two familial PAH cases in Japan with exonic deletions, finding these were Alu-mediated through different recombination processes.
- - A report of a third case involved a 25-year-old female with a unique deletion of BMPR2 exon 3, which was not linked to Alu sequences and resulted in a 759-bp deletion, suggesting it could represent a novel genetic alteration distinct from previous cases.