Publications by authors named "Yui Natusi"
Article Synopsis
- Chronic liver injury can make the liver work poorly and cause a buildup of scar tissue called fibrosis.
- Researchers found a protein called fibulin-4 that could help identify liver fibrosis in patients, especially those with cirrhosis.
- The study showed that fibulin-4 levels rise with the seriousness of cirrhosis and are linked to other problems like varices (swollen veins) in the liver.
Background: The progression of liver fibrosis leads to portal hypertension and liver dysfunction. However, no antifibrotic agents have been approved for cirrhosis to date, making them an unmet medical need. Small extracellular vesicles (sEVs) of mesenchymal stem cells (MSCs) are among these candidate agents.
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