Publications by authors named "Yuhwan Jo"

All organisms have evolved sophisticated antioxidant networks and enzymes to counteract reactive radicals, among which thioredoxin (Trx) systems are especially noteworthy. Thioredoxin domain-containing protein 17 (TXNDC17) is a ubiquitously expressed enzyme with oxidoreductase activity belonging to the Trx protein family. This study successfully uncovered and analyzed the TXNDC17 gene in Scomber japonicus (SjTXNDC17).

View Article and Find Full Text PDF
Article Synopsis
  • DDX41 is an important cytosolic DNA sensor that influences type I interferon responses, but its role in fish is not well studied.
  • Researchers identified a gene in clownfish (Amphiprion clarkii) called AcDDX41, which encodes a 617-amino-acid protein similar to DDX41 found in other species, particularly sharing a 99.68% similarity with the one in Acanthochromis polyacanthus.
  • AcDDX41 shows high expression in various tissues, especially blood, and is significantly activated under immune stimulation, indicating its role in antiviral defense and regulation of immune responses, particularly through activating the NF-κB signaling pathway.
View Article and Find Full Text PDF