Background: Pollen allergies have a high prevalence in northern China, whereas, the types of pollen allergens and population characteristics among different regions remain unclear.
Objective: To study the species and temporal distribution of the main allergenic pollen, as well as the characteristics of patients with pollen-related allergic rhinitis (AR) in different cities in northern China.
Methods: Pollen data were obtained from pollen-monitoring stations in 13 cities of northern China between 2020 and 2021.
Background: Airborne pollen is a crucial risk factor in allergic rhinitis (AR). The severity of AR symptoms can vary based on pollen type and concentration. This study aimed to estimate the association between exposure to different pollen types and AR risk.
View Article and Find Full Text PDFBackground: Artemisia pollen is the most prevalent outdoor aeroallergen causing respiratory allergies in Beijing, China. Pollen allergen concentrations have a direct impact on the quality of life of those suffering from allergies. Artemisia pollen deposition grading predictions can provide early warning for the protection and treatment of patients as well as provide a scientific basis for allergen specific clinical immunotherapy.
View Article and Find Full Text PDFThe prevalence of allergic rhinitis (AR) caused by pollen allergen is high in northern China. This study analyzed the allergen detection results of patients with AR in Beijing Tongren Hospital from 2016 to 2019, and evaluated the association between AR and seasonal airborne pollen concentration and meteorological factors in Beijing, China. We found that AR patients caused by pollen accounted for 61.
View Article and Find Full Text PDFAir pollution is associated with increased morbidity and mortality and with cell death at a cellular level. However, the exact mechanism of particulate matter-induced cell death remains to be elucidated. The aim of the present in vitro study using human alveolar epithelial cells (A549) was to determine the cell death pathway(s) induced by black carbon (BC) and ozone oxidized-black carbon (O-BC).
View Article and Find Full Text PDFWith the rapid development of urbanization, many new buildings are erected, and old ones are demolished and/or recycled. Thus, the reuse of building materials and improvements in reuse efficiency have become hot research topics. In recent years, scholars around the world have worked on improving recycle aggregates in concrete and broadening the scope of applications of recycled concrete.
View Article and Find Full Text PDFCeramsite particles are an important component of lightweight ceramsite concrete wall panels, and the density of the aggregate is much lower than the density of the slurry. It is generally accepted that there are inhomogeneities in the distribution of ceramsite particles in wall panels. Ceramsite concrete wallboard material is a research hotspot in the field of fabricated building materials at home and abroad; however, there is no effective way to quantify their inhomogeneity.
View Article and Find Full Text PDFAsian Pac J Allergy Immunol
October 2021
Background: Knowledge of the prevalence of common sensitizing allergens may aid in overall management of allergic disease in a specified area.
Objective: The aim of this study was to identify and analyse the prevalence of common inhaled and food sensitizing allergens in Beijing.
Methods: This was a retrospective study, analysing demographic data and serum sIgE antibody test results from 59057 outpatients who presented to Beijing TongRen Hospital, from January 2013 to December 2019.
Background: Air pollution may be associated with increased airway responsiveness to allergens in allergic rhinitis (AR). Ozone-aged environmental black carbon (OBC) is an important constituent of atmospheric particulate matter (PM), for which the mechanisms underlying its effects have not been fully elucidated in AR. The objective of the present study was to determine the OBC and pollen-induced alterations in the transcriptome in human nasal epithelial cells (hNECs) in vitro.
View Article and Find Full Text PDFBackground: Allergic rhinitis(AR) is an increasing challenge to public health worldwide. Exposure to environmental black carbon (BC) is associated with increased risk of allergic rhinitis, but the molecular mechanisms underlying its toxicity have not been fully elucidated. The aims of the present study were therefore to determine the effect of BC on the expression of interleukin 1β (IL-1β) and to investigate the mechanism underlying BC-induced IL-1β production in pollen-sensitized human nasal epithelial cells (hNECs).
View Article and Find Full Text PDFBackground: Artemisia annua is an important autumnal pollen allergen for seasonal allergic rhinitis (SAR) in northern China. To date, no study has investigated allergen immunotherapy with A annua. We aimed to investigate the efficacy and mechanisms underlying A annua-sublingual immunotherapy (SLIT).
View Article and Find Full Text PDFEnergy-metabolism oscillations (EMO) are ultradian biological rhythms observed in in aerobic chemostat cultures of Saccharomyces cerevisiae. EMO regulates energy metabolism such as glucose, carbohydrate storage, O uptake, and CO production. PSK1 is a nutrient responsive protein kinase involved in regulation of glucose metabolism, sensory response to light, oxygen, and redox state.
View Article and Find Full Text PDFWe monitored the type and content of airborne pollen in Haidian District, Beijing City from 2012 to 2016 by the gravity precipitation method, and analyzed the variety of pollen, peak distribution features and changes of its content, and discontinuous variation of concentration. Multiple time scale analysis was carried out for pollen concentration by the ensemble empirical mode decomposition method (EEMD). The relationship between pollen concentration and meteorological factors was analyzed.
View Article and Find Full Text PDFBackground: Grass pollen is the most prevalent sensitizing aeroallergen to cause respiratory allergies in northern China. Air pollutants have a substantial effect on respiratory health and some pollens. This study aimed to investigate relationships among airborne grass pollen, air pollutants and allergic diseases, in order to determine their effects on patients with grass pollen allergies in Beijing, China, during the period from 2013 to 2016.
View Article and Find Full Text PDFAllergic rhinitis (AR) is a disorder with high prevalence worldwide. Identification of clinically relevant allergens is the key step for the diagnosis, allergen avoidance and allergen specific immunotherapy for AR. Areas covered: With the new findings of mechanisms of AR and the development of technology, much progress has been achieved in the diagnosis of AR recently.
View Article and Find Full Text PDFAllergy Asthma Immunol Res
July 2018
Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries and currently affects up to 40% of the population worldwide. Likewise, a rising trend of AR has also been observed over the last 2-3 decades in developing countries including China, with the prevalence of AR varying widely in these countries.
View Article and Find Full Text PDFParticulate matter (PM) air pollution has been associated with an increase in the incidence of chronic allergic diseases; however, the mechanisms underlying the effect of exposure to natural ambient air pollution in chronic allergic diseases have not been fully elucidated. In the present study, we aimed to investigate the cellular responses induced by exposure to natural ambient air pollution, employing a mouse model of chronic allergy. The results indicated that exposure to ambient air pollution significantly increased the number of eosinophils in the nasal mucosa.
View Article and Find Full Text PDFMeteorological factors have been shown to affect the physiology, distribution, and amounts of inhaled allergens. The aim of this study was to develop a model to predict the trends for onset of allergic rhinitis (AR) patients. A total of 10,914 consecutive AR outpatients were assessed for the number of daily patient visits over a period of 4 years.
View Article and Find Full Text PDFObjective: To analyze the correlations between the incidence of allergic rhinitis (AR) and meteorological variables of previous periods, so as to establish non-linear prediction equations of AR in Beijing area.
Methods: AR patients (10,478 cases) collected from Beijing Tongren Hospital during 2007-2010 and meteorological data (including daily average temperature, daily maximum temperature, daily minimum temperature, daily relative humidity, daily average vapor pressure, daily dew point temperature, daily precipitation, daily average wind speed, sea level pressure, and degree of comfort) collected from Beijing Municipal Meteorological Observatory in the same periods were used for the analysis. Non-linear correlation and regression were adopted to analyze the relationship between AR incidence and meteorological variables of former six-qi stage which was defined according to Yunqi theory of Chinese medicine.
Int Forum Allergy Rhinol
January 2016
Background: Nitrogen dioxide (NO2) and sulfur dioxide (SO2) generated by excessive coal combustion and motor vehicle emissions are major air pollutants in the large cities of China. The objective of our study was to determine the effects of the exposure of oak pollens (Quercusmongolica) to several concentrations of NO2 or SO2.
Methods: Pollen grains were exposed to 0.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
April 2014
Objective: To analyze the clinical feature and treatment methods of Artemisia pollinosis.
Methods: Skin prick test results of 14 426 cases from Beijing Tongren hospital and pollen concentration of Beijing observatory from 2007 to 2011 were analyzed to identify the clinical feature of Artemisia pollinosis patients and its correlation with the pollen concentration. Patients were given leukotriene receptor antagonists (Montelukast) for 2 weeks, followed by 4 weeks of mometasone furoate nasal spray (EIT group: n = 21), or only 4 weeks of mometasone furoate nasal spray (POT group: n = 16).
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
July 2013
Objective: To analyze the correlation between meteorological factors and onset of allergic rhinitis (AR), and to establish the prediction of AR epideminlogical trend.
Methods: According to skin prick test (SPT) data of AR from Beijing Tongren Hospital and meteorological data of Beijing Observatory (2007 -2010) , analyzed the relationship between meteorological factors and onset in patients with AR. To analyze the probability distribution of onset in AR patients, and establish the grade of AR epideminlogical trend index.
Background: Short message service (SMS) has been suggested as an effective method to improve adherence to medical therapy in some chronic diseases. However, data on the effects of SMS interventions to allergic rhinitis (AR) treatment is limited at present. We aimed to assess whether a daily SMS reminder could improve AR patients' adherence to medication and treatment outcomes.
View Article and Find Full Text PDFORL J Otorhinolaryngol Relat Spec
February 2014
Objective: To evaluate the differences in clinical features and expression of cytokine thymic stromal lymphopoetin (TSLP) and its receptors in patients with eosinophilic and non-eosinophilic chronic rhinosinusitis (ECRS and NECRS).
Method: 36 ECRS patients and 50 NECRS patients were evaluated for symptoms, nasal sinus computed tomography scanning, nasal endoscopy, skin prick test (SPT) positivity, and total IgE. Expression of TSLP and receptors in ethmoid sinus mucosa from the ECRS and NECRS groups were investigated by using immunohistochemical staining.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
October 2012
Objective: To evaluate the long-term efficacy of subcutaneous immunotherapy with Dermatophagoides pteronyssinus (DerP) in patients with allergic rhinitis.
Methods: Ninety-two patients with allergic rhinitis to DerP were randomly allocated to receive either specific immunotherapy (n = 46) or medical treatment (n = 46). Symptom and medication scores and skin response to Derp were assessed to evaluate the clinical efficacy in the baseline and after three years treatment.