Publications by authors named "Yuhei Yamashita"
Providing standardized, high-quality rehabilitation for critically ill patients is a crucial issue. In 2017, the Japanese Society of Intensive Care Medicine (JSICM) promulgated the "Evidence-Based Expert Consensus for Early Rehabilitation in the Intensive Care Unit" to advocate for the early initiation of rehabilitations in Japanese intensive care settings. Building upon this seminal work, JSICM has recently conducted a rigorous systematic review utilizing the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology.
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- Heart failure with reduced ejection fraction (HFrEF) is linked to high mortality, but cardiac rehabilitation programs (CRP) can help lower rehospitalization and death rates.
- A study examined the effects of a 3-week inpatient CRP on the Metabolic Exercise data combined with Cardiac and Kidney Indexes (MECKI) scores in 53 HFrEF patients.
- Results showed an improvement in MECKI scores after the CRP, which also correlated with fewer cardiovascular events, although some patients did not see their MECKI scores improve despite experiencing these events, indicating a need for ongoing management.
The incidence of heart failure (HF) is increasing, and the mortality from HF remains high in an aging society. Cardiac rehabilitation (CR) programs (CRP) increase oxygen uptake (V̇O) and reduce HF rehospitalization and mortality. Therefore, CR is recommended for every HF patient.
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- The study aimed to establish minimum clinical practice standards for physical therapists in Japan's intensive care units (ICUs) and compare these with international standards.
- A modified Delphi method involved 54 experienced therapists rating 272 items for their essentiality, leading to 199 items being deemed essential for practice.
- The resulting standards differed from those in the UK and Australia, highlighting variations due to national laws, cultural, and historical contexts.
Germline GATA2 heterozygous mutations were identified as complex immunodeficiency and hematological syndromes characterized by cytopenia (monocytes, B-cells, NK-cells), susceptibility to mycobacterium, fungus, or Epstein-Barr virus (EBV) infection, and myelodysplastic syndrome (MDS)/acute myelogenous leukemia (AML) development. Herein, we report a patient with AML who had a fatal infection after allogeneic hematopoietic stem cell transplantation (HSCT) due to impaired immune reconstitution associated with GATA2 mutation. A 15-year-old man was diagnosed with AML with monosomy 7.
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