Publications by authors named "Yuhei Wakahara"

Article Synopsis
  • * The patient experienced significant abdominal pain and elevated eosinophils after being treated with Seprafilm, a surgical membrane, indicating a possible adverse reaction.
  • * Treatment with oral steroids led to rapid symptom improvement, suggesting a connection between the foreign body reaction to Seprafilm and the development of eosinophilic gastroenteritis.
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We have reported that the plasma zinc concentration gradually decreases with the progression of fibrosis and is related to hepatocellular carcinoma (HCC) development. The aim of this study was to examine the impact of the zinc concentration on HCC development (study 1) and the relationship between zinc intake and HCC development (study 2) in patients with hepatitis C virus (HCV) eradicated by direct-acting antivirals (DAAs). A total of 599 sustained virological response (SVR) patients treated with DAAs without a history of HCC were retrospectively analyzed in this study.

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Background And Aim: Successful eradication has been shown to prevent the development of gastric cancer (GC), but clinical evidence for factors that correlate with GC of previously -infected gastric mucosa (after eradication or natural disappearance) is limited. The purpose of our study was to identify these correlative factors.

Methods: We retrospectively examined data from patients with previously -infected gastric mucosa.

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A 70-year-old woman received H. pylori eradication therapy in March, 201X-12. She was admitted to our department because early gastric cancer was detected on esophagogastroduodenoscopy, and we performed endoscopic submucosal dissection (ESD) in June, 201X-2.

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A 51-year-old woman had been taking proton pump inhibitor since August 2008. In May, 2016, endoscopic findings showed no atrophy and no intestinal metaplasia in the stomach, and multiple fundic gland polyps were identified in the stomach. A biopsy of a pedunculated polyp measuring 10 millimeters in diameter at the greater curvature of the middle gastric body demonstrated well differentiated tubular adenocarcinoma.

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A 60-year-old man visited our department because of watery diarrhea that lasted for several months. On colonoscopy, we diagnosed him as ulcerative colitis. Additionally, a laterally spreading tumor (non-granular type) was discovered in the rectum above the peritoneal reflection (Ra).

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Objective The detection of early gastric cancer (GC) after Helicobacter pylori eradication is expected to increase in Japan. However, the predictive markers for early GC detected after H. pylori eradication have not been extensively studied.

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Aim: To investigate predictive markers for metachronous and synchronous gastric cancer (GC), which can develop after endoscopic submucosal dissection (ESD).

Methods: A total of 352 patients underwent ESD for early GC at NTT West Osaka Hospital between June 2006 and February 2016. Exclusion criteria were as follows: Remnant stomach, unknown status, and endoscopic observation of the whole stomach outside our hospital.

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Article Synopsis
  • A 62-year-old woman was hospitalized with septic shock caused by osteomyelitis and cellulitis in her lower jaw.
  • After treatment including tooth extraction and antibiotics, her condition improved but she later experienced hemorrhagic shock due to a large tarry stool.
  • An emergency EGD revealed a serious stomach ulcer that had penetrated the pancreas, but she was treated conservatively and made a full recovery within days.
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A woman in her 70s was an outpatient at our hospital. Esophagogastroduodenoscopy revealed a slightly elevated lesion with erosion, 10mm in diameter, located at the greater curvature of the antrum. Helicobacter pylori testing yielded negative results, and there was no atrophy of the gastric mucosa.

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A 79-year-old woman with a history of pyothorax was admitted with a 4-day history of abdominal distension. Physical examination revealed marked abdominal distention, absent bowel sounds, and a vesicular rash over the left Th8-10 dermatome. Abdominal radiography showed gaseous distension of the colon and ileum.

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