Publications by authors named "Yuhei Kumagai"
A chiral paddle-wheel dinuclear ruthenium catalyst was applied to a catalytic asymmetric nitrene-transfer reaction with enol silyl ethers. The ruthenium catalyst was applicable to aliphatic enol silyl ethers as well as aryl-containing enol silyl ethers. The substrate scope of the ruthenium catalyst was superior to that of analogous chiral paddle-wheel rhodium catalysts.
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- The study introduces a method for adding γ,γ,γ-trifluoroalkyl groups to quinolines using visible light, without the need for a photocatalyst.
- The process uses common alkenes and Umemoto's reagent II, allowing for the selective incorporation of various trifluoroalkyl groups via radical reactions.
- This approach provides easy access to new quinoline derivatives that can serve as valuable components in medicinal chemistry research.