A carboxymethyl cellulose-based pH-responsive chlorine dioxide release film for strawberry preservation.

Fruit spoilage caused by microorganisms results in huge economic losses and health risks worldwide every year. To develop an intelligent antimicrobial material capable of responding to the physiological activity of postharvest fruits and releasing antibacterial agents on demand, we fabricated a pH-responsive film for the release of chlorine dioxide (ClO) using carboxymethyl cellulose (CMC) and sodium chlorite (NaClO) via the solution casting method, with a CMC:NaClO ratio of 1:2 w/w. An acid environment simulated by 4 % acetic acid activated 43 % of ClO released by the film within 7 days.

Chitosan-coated liposome with lysozyme-responsive properties for on-demand release of levofloxacin.

As an anti-infection antibiotic delivery route, a drug-controlled release system based on a specific condition stimulus response can enhance drug stability and bioavailability, reduce antibiotic resistance, achieve on-demand release and improve targeting and utilization efficiency. In this study, chitosan-coated liposomes containing levofloxacin (Lef@Lip@CS) were prepared with lysozyme in body fluids serving as an intelligent "switch" to enable accurate delivery of antibiotics through the catalytic degradation ability of chitosan. Good liposome encapsulation efficacy (64.

The water extract of Amydrium sinense (Engl.) H. Li ameliorates Isoproterenol-induced cardiac hypertrophy through inhibiting the NF-κB signaling pathway.

Objective: Pathologic cardiac hypertrophy (PCH) is a precursor to heart failure. Amydrium sinense (Engl.) H.

Enzyme-responsive controlled-release materials for food preservation and crop protection - A review.

The adoption of environmentally friendly and efficient methods to control food spoilage and crop diseases has become a new worldwide trend. In the medical field, various enzyme-responsive controlled-release drug formulations have been developed for precision therapy. Recently, these materials and techniques have also begun to be applied in the fields of food preservation and agricultural protection.

A review of natural plant extracts in beverages: Extraction process, nutritional function, and safety evaluation.

The demand for foods and beverages with therapeutic and functional features has increased as a result of rising consumer awareness of health and wellness. In natural, plants are abundant, widespread, and inexpensive, in addition to being rich in bioactive components that are beneficial to health. The bioactive substances contained in plants include polyphenols, polysaccharides, flavonoids, aromatics, aliphatics, terpenoids, etc.

Preliminary Study on Rapid and Simultaneous Detection of Viable O157:H7, s, and by PMA-mPCR in Food.

O157:H7, , and are major foodborne pathogens that are widespread in nature and responsible for several outbreaks of food safety accidents. Thus, a rapid and practical technique (PMA-mPCR) was developed for the simultaneous detection of viable O157:H7, , and in pure culture and in a food matrix. To eliminate false positive results, propidium monoazide (PMA) was applied to selectively suppress the DNA amplification of dead cells.

Underlying mechanisms and molecular targets of genistein in the management of type 2 diabetes mellitus and related complications.

Diabetes mellitus (DM) is a chronic metabolic disease caused by a complex interaction of genetic and environmental factors and is characterized by persistent hyperglycemia. Long-term hyperglycemia can cause macrovascular and microvascular damage, and compromise the heart, brain, kidney, peripheral nerves, eyes and other organs, leading to serious complications. Genistein, a phytoestrogen derived from soybean, is known for its various biological activities and therapeutic properties.

Antibacterial effect and mechanism of anthocyanin from .

The inhibitory effects of the anthocyanin obtained from were tested against several food-borne pathogens were evaluated, such as (), (, and In general, anthocyanin had different antibacterial effect on different bacteria, and the best antibacterial effect on , with minimal inhibitory concentration (MIC) of 3.125 mg/mL. Anthocyanin increased the surface hydrophobicity of , discharged the intracellular K, and reduced the total soluble protein, affecting protein synthesis.