Remediation of AMD based on hydrogeochemical zonation: A typical metal mine in China.

Mining activities disrupt the natural oxidative balance underground, increasing the oxidation of metal sulfides like pyrite. This process leads to the formation of highly acidic mine drainage (AMD) with elevated concentrations of iron (Fe) and sulfate (SO). However, generic plugging and backfilling methods, when applied without considering the specific post-mining oxidative environments of different metal mines, often yields minimal results.

Nuclear Delivery of Nanoparticle-Based Drug Delivery Systems by Nuclear Localization Signals.

Nanomedicine 2.0 refers to the next generation of nanotechnology-based medical therapies and diagnostic tools. This field focuses on the development of more sophisticated and precise nanoparticles (NPs) for targeted drug delivery, imaging, and sensing.

Pd-Catalyzed Asymmetric Dearomative Arylation of Indoles via a Desymmetrization Strategy.

Pd-catalyzed asymmetric dearomative arylation of C3-substituted indoles is realized via a desymmetrization strategy. A BINOL-derived chiral phosphoramidite ligand is found to be highly efficient for the stereoselective control in this reaction. This method provides a convenient synthesis of spiroindolenines bearing two stereogenic centers in good yields (up to 98%) with excellent diastereo- and enantioselectivities (up to >20:1 dr and 97% ee), which could also be applied in asymmetric dearomative arylation of the simple C3-tethered indoles.

Compressive Behavior of Bamboo Sheet Twining Tube-Confined Concrete Columns.

This study experimentally investigated various axial compressive parameters of a new type of confined concrete, which is termed bamboo sheet twining tube-confined concrete (BSTCC). This new composite structure was composed of an outer bamboo composite tube (BCT) jacket and a concrete core. Under axial compression, the parameters of thirty-six specimens include concrete strength (i.

Palladium-catalyzed dearomative 1,4-difunctionalization of naphthalenes.

A highly diastereoselective dearomatization of naphthalenes a Pd-catalyzed 1,4-difunctionalization reaction is described. In the presence of a commercially available palladium precursor and ligand, intramolecular dearomative Heck-type insertion provides π-allylpalladium intermediates which are readily captured by a series of nucleophiles in excellent yields (up to 99%). This reaction features mild conditions, broad substrate scope, and useful transformations of the products.