Publications by authors named "Yuh Chyn Tsai"
Article Synopsis
- - The DOSE index is a tool for assessing the severity of Chronic Obstructive Pulmonary Disease (COPD) by evaluating factors like Dyspnea, Obstruction, Smoking, and Exacerbations, and shows promise in predicting healthcare costs linked to these factors.
- - A study analyzing 396 COPD cases found that higher DOSE index scores correlated with increased healthcare utilization, including more outpatient visits and higher hospitalization costs, when compared to other risk indices like BODE and ADO.
- - The research concludes that the DOSE index is effective in forecasting healthcare costs due to its focus on exacerbation frequency, emphasizing the need to consider exacerbations in COPD management.
Article Synopsis
- Governmental non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic led to a dramatic decrease in population mobility, particularly affecting transit stations, with over a 50% decline observed.
- Taiwan High Speed Rail (THSR) experienced a significant drop in operating income during the pandemic years (2020-2022), especially during the Alpha variant period, suggesting a strong link between its performance and population mobility.
- In contrast, 7-Eleven stores showed no significant changes in operating income during the same period, with their income surpassing pre-pandemic levels post-May 2022, indicating they were less affected by NPIs.
Article Synopsis
- The ADO and BODE indices are tools used to evaluate prognosis in chronic obstructive pulmonary disease (COPD), but there isn't a cost-predicting index yet.
- A study involving 396 COPD patients compared the BODE and ADO indices regarding their ability to predict medical costs and usage.
- Results showed that while both indices correlated with hospital frequency and days, the BODE index had slightly better predictive accuracy compared to ADO.
Article Synopsis
- - The study examines the prevalence of exertional desaturation (ED) in chronic obstructive pulmonary disease (COPD) patients and its connection to various clinical indexes and pulmonary function.
- - Findings reveal that COPD patients who experienced ED had reduced scores in the ADO and BODE indexes, better pulmonary function, and higher minimum oxygen saturation levels compared to non-ED patients.
- - The main conclusion is that lower minimum oxygen saturation during exercise is a significant predictor of ED, while medical costs showed no notable differences between ED and non-ED patients.
Article Synopsis
- IL13 polymorphism is linked to chronic obstructive pulmonary disease (COPD), with COPD patients showing significantly lower mitochondrial DNA copy numbers (mtDNA-CN) compared to non-COPD individuals.
- The study analyzed data from 99 COPD patients and 117 non-COPD individuals, revealing that those with IL13 CC and CT genotypes had higher mtDNA-CN than those with the TT genotype, especially among the non-COPD group.
- The results suggest that COPD may be influenced by mitochondrial regulation, indicating potential pathways for developing control methods targeting mtDNA in COPD management.
Article Synopsis
- COVID-19 emerged in late 2019 and affects children differently than adults, with lower severity and death rates; Kawasaki disease (KD) cases have surged in various regions during the pandemic.
- A total of 24 COVID-19 cases and 268 KD cases were analyzed, revealing significant differences in lab results and clinical characteristics between the two conditions in children.
- Key markers like high white blood cell counts, platelets, and procalcitonin can help distinguish between COVID-19 and KD, indicating that clinicians should monitor these levels to ensure early diagnosis of related conditions.
Article Synopsis
- The study focused on patients with prolonged mechanical ventilation (PMV), examining how abdominal weight training (AWT) and cough machine (CM) assistance impact lung function, muscle strength, and coughing ability.
- Forty PMV patients were divided into three groups: those undergoing AWT, those receiving AWT with CM support, and a control group, with significant improvements in maximum inspiratory pressure, maximum expiratory pressure, and peak cough flow observed in the AWT and AWT+CM groups compared to the control group.
- The findings suggest that AWT, especially when combined with CM assistance, can substantially enhance respiratory health and coughing effectiveness in patients with diaphragm weakness due to prolonged ventilation.
There are currently no good indicators that can be used to predict the medical expenses of chronic obstructive pulmonary disease (COPD). This was a retrospective study that focused on the correlation between the age, dyspnoea, and airflow obstruction (ADO) index and the Charlson comorbidity index (CCI) on the medical burden in COPD patients, specifically, those of patients with complete ADO index and CCI data in our hospital from January 2015 to December 2016. Of the 396 patients with COPD who met the inclusion criteria, 382 (96.
View Article and Find Full Text PDFBackground: Music intervention can reduce anxiety. This study analyzed the physiological changes from using music intervention after cardiothoracic surgery. Methods: Subjects were randomly assigned to the music group or the control group.
View Article and Find Full Text PDFUsing the BODE Index and Comorbidities to Predict Health Utilization Resources in Chronic Obstructive Pulmonary Disease.
Int J Chron Obstruct Pulmon Dis
February 2021
Background And Objective: Chronic Obstructive Pulmonary Disease (COPD) is a common chronic respiratory disease that in the long term may develop into respiratory failure or even cause death and may coexist with other diseases. Over time, it may incur huge medical expenses, resulting in a heavy socio-economy burden. The BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity) index is a predictor of the number and severity of acute exacerbations of COPD.
View Article and Find Full Text PDFBoth pulmonary function and autonomic function are impaired in patients with Parkinson's diseases (PD). This study tested the hypothesis that respiratory muscle training (RMT) can not only improve pulmonary function, but also simultaneously improve cardiovascular autonomic function and short-term functional outcomes in patients with PD. Pulmonary function was measured by the forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum inspiratory pressures (MIP), and maximum expiratory pressures (MEP).
View Article and Find Full Text PDFAmong the anti-inflammatory medications used for treating asthma, corticosteroids are the most effective. The effects of orally administered corticosteroids on intraocular pressure and lens opacity have been well defined, but the influence of inhaled corticosteroids (ICS) on children has yet to be clearly explained. Therefore, we used a nationwide cohort database to investigate glaucoma in childhood asthma patients using ICS.
View Article and Find Full Text PDFBackground: Clinically, multidrug-resistant Acinetobacter baumannii (MDR-AB) recurrence is found in some patients although identified as successfully eradicated. We aim to discover the characteristics of patients with MDR-AB recurrence in the respiratory tract.
Methods: We retrospectively collected 106 chronic respiratory failure patients with MDR-AB harvest in pulmonary secretion culture.
Background: The increased prevalence of multidrug-resistant Acinetobacter baumannii (MDRAB) poses a worldwide treatment challenge. Although aerosolized colistin therapy for MDRAB pneumonia has attracted increasing interest, factors influencing successful eradication remain unclear.
Methods: This retrospective study evaluated 135 consecutively admitted adult patients showing positive respiratory secretion cultures for MDRAB who underwent aerosolized colistin therapy between January 2007 and November 2011.
Background: Presently, the Department of Health Taiwan has begun to fund a smoking cessation program, and the annual cessation rate was 8.9% in 2010. This study aims to see whether to enhance abstinence effectiveness by utilizing exhaled carbon monoxide (COExh) measurement with self-declared smoking cessation.
View Article and Find Full Text PDFAlthough many parameters were investigated about weaning and mortality in critical patients in intensive units, no studies have yet investigated predictors in prolonged mechanical ventilation (PMV) patients following successful weaning. A cohort of 142 consecutive PMV patients with successful weaning in our respiratory care center was enrolled in this study. Successful weaning is defined as a patient having smooth respiration for more than 5 days after weaning.
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