Publications by authors named "Yugang Lin"
Knowledge-based in silico fragmentation and annotation of mass spectra for natural products with MassKG.
Comput Struct Biotechnol J
December 2024
Article Synopsis
- Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is used to identify natural products, but the complex structures of these products make data analysis challenging.
- A new algorithm called MassKG has been developed, which utilizes a combination of knowledge-based fragmentation and deep learning to streamline the identification of natural product structures.
- MassKG has already compiled a vast database of known natural products and generated new potential compounds, showing superior performance in data annotation and is available online with features that improve usability for researchers.
Ethnopharmacological Relevance: Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes. Mudan granules (MD) is a Chinese patent medicine for treating DPN, which is composed of nine Chinese medicinal herbs, including the radix of Astragalus membranaceus (Fisch.) Bge.
View Article and Find Full Text PDFLumpy skin disease virus (LSDV) is a rapidly emerging pathogen in Asia, including China. Improving the propagation of LSDV is important for diagnostics and vaccine production. Our study identified and compared the LSDV susceptibility of eleven standard cells using western blot, indirect immune-fluorescence assay, quantitative PCR, and 50 % tissue culture infectious dose.
View Article and Find Full Text PDFGinkgo biloba L. leaf (GBL) is one of the most commonly used medicinal plants in the world. Phenolic acids with biological activities have a relatively high content in G.
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