Publications by authors named "Yugang Guan"
CNS Neurosci Ther
September 2023
Article Synopsis
- - Deep brain stimulation (DBS) of the anterior thalamus is a promising treatment for drug-resistant epilepsy, potentially working by increasing adenosine levels and modulating adenosine pathways.
- - In a study with rats, DBS significantly reduced seizure frequency and interictal epileptic discharges compared to control and sham-DBS groups, suggesting its effectiveness in managing epilepsy.
- - The results indicate that DBS may exert its effects by inhibiting adenosine kinase (ADK) and activating A1 receptors, pointing to these pathways as potential targets for further epilepsy treatments.
