The peptide arginine-proline-arginine (RPR) has potential benefits for treating lifestyle-related diseases, particularly in reducing fat accumulation in the liver.
In experiments with HepG2 cells, RPR significantly lowered triglyceride levels when combined with oleic acid, compared to oleic acid alone.
The study concludes that RPR's positive effects on liver fat reduction are mediated through the peptide transporter 1 (PepT1) pathway.