Publications by authors named "Yufu Zheng"
Article Synopsis
- Immunotherapy can be effective for cancer, but many osteosarcoma patients don't benefit from it due to the unique characteristics of their tumor environment, like hypoxia and lactate metabolism, which may predict treatment outcomes.
- Researchers identified a set of 8 genes linked to these environmental factors and created a nomogram to assess patient risk; those with high-risk scores showed worse prognoses and a lack of immune cell activity in tumors.
- Analysis indicated that high-risk patients had lower levels of essential immune cells (e.g., Cytotoxic T cells) and immune markers, suggesting they are less likely to respond well to immunotherapy.
Fabrication of Magnetic Poly(L-lactide) (PLLA)/FeO Composite Electrospun Fibers.
Materials (Basel)
August 2024
Electrospinning technology is widely used for preparing biological tissue engineering scaffolds because of its advantages of simple preparation, accurate process parameters, and easy control. Poly(L-lactide) (PLLA) is regarded as a promising biomass-based polymer for use in electrospinning. The incorporation of FeO nanoparticles (NPs) could improve the osteogenic differentiation and proliferation of cells in the presence or absence of a static magnetic field (SMF).
View Article and Find Full Text PDFPyroptosis is a programmed cell death process mediated by the gasdermin (GSDM) protein. However, limited research has been conducted to comprehensively analyze the contribution of the GSDM family in a pan-cancer setting. We systematically evaluated the gene expression, genetic variations, and prognostic values of the GSDM family members.
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