Publications by authors named "Yufeng Gao"

The aim of this study was to evaluate the effect of different Angle printing on the model on the printing platform and whether it affects the later transfer accuracy. Ten bracket transfer models were printed on the platform of the 3D printer in four ways: 0° without support rod, 0°, 45° and 90° with support rod. Transfer guide plates for transfer brackets were made using PVS.

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The investigation of two-dimensional materials exhibiting half-metallicity and topological features has become a rapidly growing area of interest, driven by their immense potential in nanoscale spintronics and quantum electronics. In this work, we present a comprehensive study of a two-dimensional PrClS monolayer, revealing its remarkable electronic and mechanical properties. Under its ferromagnetic ground state, the PrClS monolayer is shown to exhibit half-metallic behavior with 100% spin polarization originating from the spin-up channel.

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The slight structural differences between carbohydrate isomers pose considerable difficulties for their identification and quantification. Herein, a rapid method for the absolute quantification of glucose and fructose isomers using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight tandem mass spectrometry (MALDI-TOF/TOF MS/MS). A novel reagent, 4-trimethylamino-6-(4-methoxy-1-naphthyl)-1,3,5-triazine-2-(3-aminophenylboronic acid) (TMNTA), was synthesized and employed as a reactive matrix.

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Background: Malaria is a major health risk faced by Chinese expatriates working in South Sudan. The purpose of this study is to investigate the knowledge, attitudes and practices (KAP) of Chinese expatriates in South Sudan towards malaria prevention and control, analyze the influencing factors, and provide a basis for reducing the morbidity and mortality of malaria.

Methods: By distributing questionnaires, data on socio-demographic characteristics of Chinese expatriates in South Sudan, and information on their knowledge, attitudes, and behaviors towards malaria prevention and control were collected from April 5th to 12th, 2023.

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The objective was to study the subcritical crack growth phenomena and determine the fracture toughness of two yttria-partially-stabilized zirconia ceramics. One of the two materials evaluated was a commercially available 5 mol% yttria partially stabilized zirconia (5Y-PSZ), and the other was an experimental partially stabilized zirconia made from a mixture of 3 mol% and 8 mol% yttria stabilized zirconia powder (3Y+8Y-PSZ), with the final samples prepared by the Stereolithography (SLA) process. The samples in water were tested by three-point bending experiments at different stress rates to obtain Weibull and SCG parameters.

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Optical tweezers and related techniques offer extraordinary opportunities for research and applications in physical, biological, and medical fields. However, certain critical requirements, such as high-intensity laser beams, sophisticated electrode designs, additional electric sources, or low-conductive media, significantly impede their flexibility and adaptability, thus hindering their practical applications. Here, we report innovative photopyroelectric tweezers (PPT) that combine the advantages of light and electric field by utilizing a rationally designed photopyroelectric substrate with efficient and durable photo-induced surface charge-generation capability, enabling diverse manipulation in various working scenarios.

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Background: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver condition in children, underscoring the urgent need for non-invasive markers for early detection in this population.

Methods: We utilized survey data from the National Health and Nutrition Examination Survey (NHANES) 2017-2020 regarding liver ultrasound transient elastography (LUTE) for the diagnosis of NAFLD (dependent variable), and used multiple logistic regression models to explore the association between weight-adjusted waist circumference index (WWI) and the prevalence of NAFLD in US adolescents. Smoothing curves and threshold effect analyses were used to assess the non-linear association between the independent variables and the dependent variable.

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Natural extracellular matrices (ECM) provide a more accurate simulation of the cellular growth environment, making them excellent substrate materials for in vitro cell culture. The porcine small intestinal submucosa (SIS) is one of the most widely used natural ECM that display superior bioactivity. However, decellularization operations often result in fiber breakage and failure to recover mechanical strength in the SIS.

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Two-dimensional van der Waals (vdW) layered materials not only are an intriguing fundamental scientific research platform but also provide various applications to multifunctional quantum devices in the field-effect transistors (FET) thanks to their excellent physical properties. However, a metal-semiconductor (MS) interface with a large Schottky barrier causes serious problems for unleashing their intrinsic potentials toward the advancements in high-performance devices. Here, we show that exfoliated vdW Dirac semimetallic PtTe can be an excellent electrode for electrons in MoS FETs.

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Cancer-associated fibroblasts (CAFs) are essential players in the tumor microenvironment (TME) due to their roles in facilitating tumor progression and metastasis. It is worth noting that the high-metastatic hepatocellular carcinoma (HCC) cell-derived exosomes have exhibited the ability to transform normal fibroblasts into CAFs, which further fosters the lung metastasis of low-metastatic HCC cells. Yet, the mechanisms underlying this tumor exosome-induced metastatic niche formation are poorly explored.

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Background: White granulated sugar, a significant commodity in bulk trade and widely used raw material, plays a crucial role in the food, energy, and medicine industries. A certified reference material (CRM) of white granulated sugar provides a valuable tool for monitoring and maintaining the safety and quality of white granulated sugar and other related products. The colorimetric value, conductivity ash, sucrose content, and reducing sugar content serve as essential factors that determine the quality of white granulated sugar.

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Background: This study aimed to analyze the effect of 3D printing temporary crowns on the single and continuous loss restoration of posterior teeth during secondary implant surgery.

Methods: This study adopted a single-center, randomized, single-blind, parallel-controlled trial design. Thirty patients who were admitted to the Department of Stomatology, Affiliated Hospital of Jiangnan University between January 2020 and February 2023 and who had >2 consecutive missing posterior teeth were implanted with the same implant system.

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Enzyme-induced carbonate precipitation (EICP) has been studied in the remediation of heavy metals in recent years. This study aims to investigate the impact of EICP with jack bean urease (JU) and sword bean urease (SU) on the Zn remediation. The results show that relatively high concentration of organic molecules in SU can protect urease from deactivation and absorb Zn.

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Active faults along railways in the mountainous regions of western China pose significant challenges to bridge safety. To ensure the safe operation of long-span railway bridges under complex geological conditions, this study investigates the synthesis of artificial ground motions for bridges crossing strike-slip faults and analyzes their nonlinear seismic response. First, we develop a theoretical method for simulating high- and low-frequency seismic motions using a finite fault and an equivalent velocity pulse model.

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Objectives: This study evaluated the impact of self-management interventions based on the COM-B model on peri-implant conditions in older adults with periodontitis.

Materials And Methods: The patients were randomly divided into two groups: Group 1 (control group) received only an oral health education (OHE) pamphlet. Group 2 (test group) performed a self-management intervention based on the COM-B model.

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Background: The progression of chronic hepatitis B (CHB) to liver fibrosis and even cirrhosis is often unknown to patients, but noninvasive markers capable of effectively identifying advanced liver fibrosis remains absent.

Objective: Based on the results of liver biopsy, we aimed to construct a new nomogram to validate the stage of liver fibrosis in CHB patients by the basic information of CHB patients and routine laboratory tests.

Methods: Patients with CHB diagnosed for the first time in the First Affiliated Hospital of Anhui Medical University from 2010 to 2018 were selected, and their basic information, laboratory tests and liver biopsy information were collected.

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T lymphocyte therapies demonstrate significant promise in the treatment of cancer and infectious diseases. An efficient gene delivery system is essential for the safe and reliable introduction of exogenous genes, especially mRNA, into cells to achieve therapeutic purposes. Commercial transfection reagents are suitable for the transduction of plasmids to adherent cells, whereas they are ineffective for suspension cells such as T lymphocytes and for unstable mRNA.

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Targeting the PD-1/PD-L1 axis with small-molecular inhibitors is a promising approach for immunotherapy. Here, we identify a natural pentacyclic triterpenoid, Pygenic Acid A (PA), as a PD-1 signaling inhibitor. PA exerts anti-tumor activity in hPD-1 knock-in C57BL/6 mice and enhances effector functions of T cells to promote immune responses by disrupting the PD-1 signaling transduction.

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Background: Legionella maceachernii pneumonia is a severe respiratory infection with low incidence but high mortality. However, the optimal treatment for this disease remains unclear. We report a case of successful treatment of Legionella maceachernii pneumonia, which is the first report of such a case in China.

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Background: Severe fever with thrombocytopenia syndrome (SFTS) is spreading rapidly in Asia. The pathway of SFTS virus shedding from patient and specific use of personal protective equipments (PPEs) against viral transmission have rarely been reported. The study was to determine SFTS virus (SFTSV) shedding pattern from the respiratory, digestive and urinary tract to outside in patients.

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Article Synopsis
  • Enzyme-induced carbonate precipitation (EICP) is being explored for cleaning up heavy metal contamination in soil and water, focusing on the roles of Zn, Ni, and Cr(VI) in contaminated sand using urease from sword beans.
  • The study found that increased calcium levels improved heavy metal immobilization percentages, achieving impressive results after several treatment cycles: nearly complete immobilization of Zn and significant percentages for Ni and Cr(VI).
  • Analytical methods revealed the formation of carbonate precipitates and metallic oxides during the process, supporting the idea that EICP works through biomineralization, adsorption, and complexation, while simultaneously increasing the strength of the treated sand.
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Background: The manipulation of compliant objects by robotic systems remains a challenging task, largely due to their variable shapes and the complex, high-dimensional nature of their interaction dynamics. Traditional robotic manipulation strategies struggle with the accurate modeling and control necessary to handle such materials, especially in the presence of visual occlusions that frequently occur in dynamic environments. Meanwhile, for most unstructured environments, robots are required to have autonomous interactions with their surroundings.

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Article Synopsis
  • Recent research suggests proton pump inhibitors (PPIs) may enhance the effectiveness of immune checkpoint inhibitors (ICIs) by increasing PD-L1 expression on tumor cells, although their effect on microbiome diversity is also a concern.
  • In experiments with mice, PPIs were found to boost PD-L1 levels at the cell membrane without changing total protein levels, and they worked synergistically with anti-PD-L1 antibodies to improve tumor response.
  • Clinical data from esophageal cancer patients showed that those using PPIs exhibited higher PD-L1 expression in tumor tissues, indicating a potential link between PPI use and altered immune response in cancer.
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