Publications by authors named "Yufei Lou"

Objective: Previous research suggests a correlation between nontoxic goitre and type 2 diabetes mellitus (T2DM). However, the causality was vulnerable to confounding variables. Therefore, there is an urgent need for a more rigorous research approach to examine the causal connection between nontoxic goitre and T2DM.

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Purpose: To evaluate literature evidences about the efficacy and safety of anti-angiogenesis agents plus chemoradiotherapy versus chemoradiotherapy in the treatment of locally advanced nasopharyngeal carcinoma.

Methods: The relevant literature was systematically searched from the date of establishment to April 2023 in PubMed, Embase, Web of Science, The Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Biological Medicine, Wanfang and VIP database. Search terms included: Nasopharyngeal Neoplasms, Angiogenesis inhibitors, Endostar, Anlotinib, Apatinib, Bevacizumab, Sunitinib, Pazopanib, Chemoradiotherapy.

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Background: There is increasing evidence that neoadjuvant chemoradiotherapy is superior to neoadjuvant chemotherapy for patients with locally advanced gastric cancer. However, a number of studies have come to the opposite conclusion. Therefore, our meta-analysis is to evaluate the efficacy and safety of neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy in the treatment of locally advanced gastric cancer.

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Article Synopsis
  • Chicken infectious anemia (CIA) is a viral disease in chickens that leads to stunted growth and weakened immune systems, resulting in severe economic impacts on the poultry industry.
  • A study collected and analyzed 854 samples from 13 cities in Shandong Province, China, from 2020 to 2022, revealing a 17.21% infection rate in 2020, which decreased slightly in subsequent years.
  • The analysis showed most infected strains were of genotype A, with minimal genetic variation, indicating a common prevalence of CIA and mixed infections with other viruses in recent years.
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The short-lived African killifish is an attractive genetic model for vertebrate aging and regeneration studies. The utilization of genetically modified animals is a common strategy for unveiling molecular mechanisms responsible for a biological phenomenon. Here, we report a highly efficient protocol for generating transgenic African killifish using the Tol2 transposon system, which creates random insertions in the genome.

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Article Synopsis
  • * IgE antibodies play a significant role in BP, leading researchers to explore anti-IgE treatments like omalizumab, which has shown promise in clinical applications.
  • * Analysis of 35 studies involving 83 patients indicated that most experienced improvements with omalizumab treatment, though the frequency of dosing had minimal impact on effectiveness, while the total number of doses influenced outcomes without a clear correlation.
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Objectives: Androgen deprivation therapy combined with radiotherapy for intermediate-risk prostate cancer is still a matter of debate. We conducted a meta-analysis to evaluate the necessity of androgen deprivation therapy combined with radiotherapy for intermediate-risk prostate cancer patients.

Methods: A comprehensive literature search of articles was performed in PubMed, Embase, Cochrane library, Web of Science, Chinese National Knowledge Infrastructure, Chinese Biological Medicine, Wanfang, and VIP Databases published between February 1988 and April 2022.

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  • A study was conducted to assess the presence of avian hepatitis E virus (HEV) in healthy chickens across 12 farms in Tai'an City, China, where researchers collected cloacal swabs and yolk samples.
  • The results showed positive rates for HEV in cloacal swabs (6.25%) and yolk samples (4.51%), with higher rates found in chicks (11.67%) and various stages of embryos from breeder farms, indicating potential vertical transmission.
  • Genetic analysis revealed the isolated strains were distinct, with 76.4% to 83.9% nucleotide homology to existing genotypes, suggesting the presence of novel genotypes of avian HEV in the area.
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Objectives: To compare the survival and complications of neoadjuvant chemoradiation (NCRT) versus neoadjuvant chemotherapy (NCT) for esophageal squamous cell carcinoma (ESCC).

Methods: We conducted a systematic literature search of the PubMed, Web of Science, Cochrane Library, EMBASE, CNKI, Wanfang Data, CBM, and VIP databases from inception to November 2021. Meta-analyses were performed using RevMan (version 5.

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