Publications by authors named "Yueyuan Wu"
Objective: Sepsis is characterized by high incidence and mortality rates, making early recognition and risk stratification critical for preventing delayed treatment and overtreatment. This study investigated the potential of monocytic (m) HLA-DR as a diagnostic and prognostic biomarker of sepsis.
Methods: In this prospective study, we collected blood in EDTA-anticoagulated tubes within 48 h from patients diagnosed with sepsis or infection and analyzed the percentage of mHLA-DR in peripheral blood mononuclear cells, C-reactive protein, and procalcitonin within 2 h of collection.
Genetic Polymorphism of E2F1 Influences Susceptibility to Ovarian Cancer in a Chinese Population.
Contrast Media Mol Imaging
July 2022
Purpose: The present study is aimed at exploring whether rs3213172, rs3213173, and rs3213176 polymorphisms of the E2F1 gene confer risk for ovarian cancer.
Methods: A total of 80 patients with ovarian cancer were selected from the first affiliated hospital of Soochow University in Jiangsu Province from January 2016 to June 2021, including 48 cases that were premenopausal and 32 cases that were menopausal. 130 healthy women who participated in normal physical examinations during the same period were selected as the control group.
Article Synopsis
- Brucellosis is a zoonotic infection linked to contact with infected animals, and genetic variations in IL-10 and IL-6 may influence susceptibility to the disease.
- A meta-analysis showed that the -819 genetic polymorphism in IL-10 is significantly associated with reduced risk of Brucellosis specifically in Asian populations, while other polymorphisms did not show an association.
- Overall, the findings suggest that certain IL-10 genetic variations may lower Brucellosis risk in Asians, but not in Caucasians, and other studied polymorphisms have no impact on the disease's risk.