The Air Pollution Prevention and Control Action Plan (APPCAP) is considered to be the most stringent air pollution control policy in China implemented since 2013. This policy is a milestone in China to mitigate serious air pollution. However, health benefits attributable to reduced fine-particulate air pollution after the implementation of the APPCAP have not been quantitatively estimated on a PM constituent-specific and morbidity cause-specific basis.
View Article and Find Full Text PDFBackground: In the context of global warming, the frequency of heat wave and the concentration of fine particulate matter (PM) have increased, and more people are co-exposed to air pollution and extreme heat. However, the interaction between heat wave and PM on cardiovascular disease (CVD) mortality remained largely unknown.
Methods: We conducted a time-stratified case-crossover study of 40,169 CVD deaths in Shenzhen, China between 2013 and 2022.
Extensive studies have identified potential adverse effects on semen quality of obesity, based on body mass index, but the association between body fat distribution, a more relevant indicator for obesity, and semen quality remains less clear. We conducted a longitudinal study of 4304 sperm donors from the Guangdong Provincial Human Sperm Bank (Guangzhou, China) during 2017-2021. A body composition analyzer was used to measure total and local body fat percentage for each participant.
View Article and Find Full Text PDFIntroduction: Gestation is a critical period for fetal brain development, and extreme heat exposure during this stage may have adverse impact on neurodevelopment in children. However, current evidence is scarce.
Methods: We examined the associations between maternal exposure to heat wave during pregnancy and neurodevelopmental delay in young children in a birth cohort study of 67,453 child-mother pairs from Foshan, China.
Background And Objective: Evidence of short-term exposure to particulate matter with an aerodynamic diameter ≤1 μm (PM) on hospital admission for respiratory diseases (RDs) is limited. We aimed to estimate the associated risk of PM on hospital admissions for RDs.
Methods: In this time-stratified case-crossover study, we assigned cases who had been admitted to hospital for RDs in Guangdong, China between 2016 and 2019.
Previous studies have illustrated the pivotal role of coagulation biomarkers in the link between air pollution and cardiovascular disease (CVD). However, inconsistencies remain in the conclusions, with limited studies conducted in rural areas of China. We conducted a panel study in rural areas of Henan Province, China.
View Article and Find Full Text PDFInterstitial lung diseases (ILDs) lead to increased morbidity and premature deaths, imposing a significant burden on public health worldwide. Recently, several studies have linked ambient air pollution with the acute exacerbation of certain ILDs, but the evidence remains limited and inconclusive. With a multicenter hospital-based case-crossover design, we investigated 9128 patients who resided in Jiangsu province, China, and were admitted for ILDs between 2019 and 2022.
View Article and Find Full Text PDFShort-term ambient fine particulate matter (PM) exposure has been related to an increased risk of myocardial infarction (MI) death, but which PM constituents are associated with MI death and to what extent remain unclear. We aimed to explore the associations of short-term exposure to PM constituents with MI death and evaluate excess mortality. We conducted a time-stratified case-crossover study on 237,492 MI decedents in Jiangsu province, China during 2015-2021.
View Article and Find Full Text PDFMicro-LiNiCoMnO (MNCM), a cathode material with highest market share, has increasing demand with the growth of lithium battery industry. However, whether MNCM exposure brings adverse effects to workers remains unclear. This study aimed to explore the association between MNCM exposure with systemic inflammation and cardiac function.
View Article and Find Full Text PDFThe continuous decline of human semen quality during the past decades has drawn much concern globally. Previous studies have suggested a link between abnormal BMI and semen quality decline, but the results remain inconsistent. This systematic review and meta-analysis aimed to evaluate the association between body mass index (BMI) and semen quality.
View Article and Find Full Text PDFGlucose metabolic disorders, prevalent in numerous metabolic diseases, have become a pressing global public health concern. Artemisinin (ART) and its derivatives, including artesunate (ARTs) and artemether (ARTe), have shown potential as metabolic regulators. However, the specific effects of ART and its derivatives on glucose metabolism under varying nutritional conditions and the associated molecular mechanisms remain largely unexplored.
View Article and Find Full Text PDFBackground: The short-term adverse effects of ambient fine particulate matter (PM) and ozone (O) on anxiety disorders (ADs) remained inconclusive.
Methods: We applied an individual-level time-stratified case-crossover study, which including 126,112 outpatient visits for ADs during 2019-2021 in Guangdong province, China, to investigate the association of short-term exposure to PM and O with outpatient visits for ADs, and estimate excess outpatient visits in South China. Daily residential air pollutant exposure assessments were performed by extracting grid data (spatial resolution: 1 km × 1 km) from validated datasets.
Equilibration of metal metabolism is critical for normal liver function. Most epidemiological studies have only concentrated on the influence of limited metals. However, the single and synergistic impact of multiple-metal exposures on abnormal liver function (ALF) are still unknown.
View Article and Find Full Text PDFIndividuals with cardiovascular disease (CVD) are particularly vulnerable to dementia, but it remains unclear whether air pollution exposure links with higher risk of dementia among those with CVD. The data were derived from the UK Biobank study (UKB). Dementia-free participants with CVD at baseline were included.
View Article and Find Full Text PDFBenefiting from the unique photoluminescence behavior of the lanthanide(III) ions and organic ligands, a lanthanide(III) metal-organic framework (Ln-MOF) material can simultaneously demonstrate photoluminescence of lanthanide(III) cations and organic molecules and endow its superior applications of fluorescence sensing behaviors. Herein, we present a europium(III) MOF material {[Eu(BPTA)·(CHCOO)·3DMA]·0.5DMA·3HO} () (where HBPTA is 3,3',5,5'-biphenyltetracarboxylic acid) for photoluminescence performance of quantitatively sensing the inflammatory marker neopterin (Neo).
View Article and Find Full Text PDFIn recent years, there has been growing concern about the adverse effects of endocrine disrupting chemicals (EDCs) on male fertility. Epigenetic modification is critical for male germline development, and has been suggested as a potential mechanism for impaired fertility induced by EDCs. Bisphenol A (BPA) has been recognized as a typical EDC.
View Article and Find Full Text PDFA two-dimensional (2D) mathematical model of quadratically distorted (QD) grating is established with the principles of Fraunhofer diffraction and Fourier optics. A discrete sampling method is applied for finding a numerical solution of the diffraction pattern of QD grating. An optimized working phase term, which determines the balanced energies and high efficiency of multi-plane images, can be obtained by the bisection algorithm.
View Article and Find Full Text PDFBackground: Ambient fine particulate matter (PM) exposure has been associated with an increased risk of gastrointestinal cancer mortality, but the attributable constituents remain unclear.
Objectives: To investigate the association of long-term exposure to PM constituents with total and site-specific gastrointestinal cancer mortality using a difference-in-differences approach in Jiangsu province, China during 2015-2020.
Methods: We split Jiangsu into 53 spatial units and computed their yearly death number of total gastrointestinal, esophagus, stomach, colorectum, liver, and pancreas cancer.
A case-crossover study among 511,767 cardiovascular disease (CVD) deaths in Jiangsu province, China, during 2015-2021 was conducted to assess the association of exposure to ambient ozone (O) and heat wave with CVD mortality and explore their possible interactions. Heat wave was defined as extreme high temperature for at least two consecutive days. Grid-level heat waves were defined by multiple combinations of apparent temperature thresholds and durations.
View Article and Find Full Text PDFThis study examined the associations of long-term exposure to ambient fine particulate matter (PM) compositions/ozone with methylation of peripheral brain-derived neurotrophic factor (BDNF) promoters. A total of 101 participants were recruited from a cohort in Shijiazhuang, Hebei province, China. They underwent baseline and follow-up surveys in 2011 and 2015.
View Article and Find Full Text PDFCauses of autism spectrum disorder (ASD) have not been fully understood. Previous studies have linked environmental factors with ASD. However, evidence for the greenness-ASD association is limited, especially in China.
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