Carbapenem-resistant : A challenge in the intensive care unit.

Carbapenem-resistant (CRAB) has become one of the leading causes of healthcare-associated infections globally, particularly in intensive care units (ICUs). Cross-transmission of microorganisms between patients and the hospital environment may play a crucial role in ICU-acquired CRAB colonization and infection. The control and treatment of CRAB infection in ICUs have been recognized as a global challenge because of its multiple-drug resistance.

Emergence of a Hypervirulent Tigecycline-Resistant Strain Co-producing and With an Uncommon Sequence Type ST464 in Southwestern China.

Emergence of and co-producing strains is currently attracting widespread attention, but little information is available about their tigecycline resistance, virulence, and prevalence in Southwest China. In July 2021, an extensively drug-resistant strain AHSWKP25 whose genome contained both and genes was isolated from the blood of a patient with the malignant hematological disease in Luzhou, China. We investigated the resistance profiles of AHSWKP25 using microbroth dilution, agar dilution, modified carbapenemase inactivation (mCIM), and EDTA-modified carbapenemase inactivation methods (eCIM).

Genomic and Phenotypic Characterization of a Colistin-Resistant Isolate Co-Harboring , and Isolated from Urine.

Background: Colistin is one of the few options for treating carbapenem-resistant Enterobacterales (CREs). There is little available information about the epidemic status of colistin-resistant CREs in Southern Sichuan, China. This study mainly investigated the genomic and phenotypic characteristics of an extensively drug resistant LZ00114 isolated from Luzhou, China.