Publications by authors named "Yueshen Wang"
Background And Objective: Hemodynamic changes that lead to increased blood pressure represent the main drivers of organ damage in hypertension. Prolonged increases to blood pressure can lead to vascular remodeling, which also affects vascular hemodynamics during the pathogenesis of hypertension. Exercise is beneficial for relieving hypertension, however the mechanistic link between exercise training and how it influences hemodynamics in the context of hypertension is not well understood.
View Article and Find Full Text PDFBackground: Exercise training protects against heart failure. However, the mechanism underlying the protective effect of exercise training on angiotensin II (Ang II)-induced cardiac fibrosis remains unclear.
Methods: An exercise model involving C57BL/6N mice and 6 weeks of treadmill training was used.
Article Synopsis
- Acupuncture and related therapies are shown to be effective in treating patients with mild to moderate Alzheimer's disease (AD), with a focus on comparing various interventions.
- A network meta-analysis of 36 studies involving 2712 patients found that acupuncture combined with cognitive training had the highest effectiveness in improving cognitive function compared to other therapies.
- The findings suggest that the best therapies include acupuncture combined with training, and using different combinations of acupuncture with other therapies may provide additional benefits for Alzheimer's patients.
Article Synopsis
- * Researchers conducted a Network Meta-Analysis to gather and analyze data from multiple randomized controlled trials, utilizing various databases and software tools.
- * Findings aim to provide insights into the best acupuncture treatments for hyperlipidemia, offering valuable information for patients, clinicians, and guidelines on effective therapy options.
Article Synopsis
- The study aimed to assess how electroacupuncture at specific points (Baihui and Shenshu) affects the expression of proteins related to autophagy in the hippocampus of rats with Alzheimer's disease.
- A total of 48 male rats were divided into four groups, including a model group that received D-galactose to induce Alzheimer's, with some receiving actual electroacupuncture and others receiving sham treatment.
- Results showed that the model group experienced worse cognitive performance and lower synapse density, along with increased levels of certain autophagy-related proteins, compared to the control group, indicating the potential benefits of electroacupuncture in improving Alzheimer's symptoms.
Article Synopsis
- The study aimed to evaluate the effects of pre-exercise acupuncture at specific points (Neiguan and Zusanli) on reducing fatigue in participants.
- Fifty subjects were randomly assigned to an observation group (receiving acupuncture) and a control group (no treatment), with various measurements taken before and after exercise.
- Results showed that the observation group experienced significantly lower fatigue scores, lactate levels, and heart rates after exercise compared to the control group, suggesting acupuncture may help alleviate exercise-induced fatigue.
Haemodynamic disorders are common clinical findings in hypertension and lead to adverse cardiovascular events. However, the haemodynamic conditions in hypertension models are poorly understood. This study aimed to observe the characteristics of haemodynamics in spontaneously hypertensive rats (SHRs) and antihypertensive-treated SHRs.
View Article and Find Full Text PDFWe evaluated the efficacy and feasibility of the combination of gemcitabine plus vinorelbine in patients with platinum-based chemotherapy-refractory esophageal cancer. We enrolled 35 patients who received gemcitabine plus vinorelbine as second-line treatment after platinum-based chemotherapy failure between May 2009 and April 2012. Dosage: gemcitabine 1,000 mg/m(2) plus vinorelbine 25 mg/m(2); all drugs were administered on days 1 and 8 of a 21-day cycle, and this was continued until failure or unacceptable toxicity.
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