1550 Nm Optical Coherence Tomography for In Vivo Deep Brain Cerebral Blood Flow Imaging.

Employing longer wavelengths in optical microscopic imaging is recognized for its advantage in deep penetration. However, the 1550 nm spectrum band is often overlooked due to water's high absorption coefficient. This study investigates the feasibility of 1550 nm center wavelength-based optical coherence tomography (OCT) for imaging the cerebral vasculature and blood flow in the mouse brain cortex.