Publications by authors named "Yueqi Shen"

Background: Schizophrenia (SCZ) is a mental disorder that can cause severe disability, including impairment of social cognition, which is considered a core feature of SCZ, and the Theory of Mind (ToM) is a core component of social cognition. Although many studies have confirmed the presence of ToM impairment in patients with SCZ, its characteristics in terms of different orders (first-order and second-order) and components remain unclear, and no studies have investigated the independent correlations between such impairment and clinical symptoms. Therefore, this study aimed to identify the characteristics of ToM impairment in patients with SCZ.

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Article Synopsis
  • The robust meta-analytical-predictive (rMAP) prior is an effective method for utilizing external data, but it requires pre-defining a mixture coefficient, which can be difficult during study design.
  • The new empirical Bayes robust MAP (EB-rMAP) prior improves upon this by adaptively incorporating external data based on actual study needs while balancing model simplicity and flexibility.
  • Simulation results show that the EB-rMAP prior is effective at handling prior-data conflicts and maintaining statistical power, and it has been successfully tested on data from 10 oncology clinical trials.
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Identification of patients at risk of deteriorating during their hospitalization is an important concern. However, many off-shelf scores have poor in-center performance. In this article, we report our experience developing, implementing, and evaluating an in-hospital score for deterioration.

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In this paper, a two-step resin adsorption technology was investigated for spinosad production and separation as follows: the first step resin addition into the fermentor at early cultivation period to decrease the timely product concentration in the broth; the second step of resin addition was used after fermentation to adsorb and extract the spinosad. Based on this, a two-step macroporous resin adsorption-membrane separation process for spinosad fermentation, separation, and purification was established. Spinosad concentration in 5-L fermentor increased by 14.

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