Publications by authors named "Yueping Zeng"

Article Synopsis
  • The study investigates Epstein-Barr virus-associated lymphoproliferative disorders (EBV-LPDs) in hospitalized children in China, focusing on their epidemiology and economic impact from 2016 to 2021.
  • Data was analyzed from 27 children's hospitals, examining five specific types of EBV-LPDs, looking at factors like demographics, hospitalization costs, length of stay, and complications.
  • Results showed that 153 children were hospitalized, with the majority aged 6-12 years, and highlighted that EBV T-LPDs were the most common type, while complications such as hemophagocytic lymphohistiocytosis were prevalent, emphasizing the significant healthcare costs associated with these disorders.
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Article Synopsis
  • Melanocytic nevi commonly appear in children and their surgical removal is frequent, yet detailed data on hospitalization trends for these cases has been limited.
  • A study analyzed records of 13,396 pediatric inpatients in China, revealing that most cases were boys aged 7-12 from urban areas, with common lesion sites on the buttocks and lower limbs.
  • The findings highlighted a significant hospitalization burden influenced by patient age, lesion location, and surgical methods, indicating a need for increased governmental attention and support for this pediatric group.
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Background: Transport accidents are one of the leading causes of child morbidity and mortality worldwide and represent a significant public health burden. This study aimed to investigate the hospitalization information and burden of pediatric inpatients in transport accidents in China.

Methods: In this study, we collected the cover page of the medical records of pediatric inpatients in transport accidents using the Futang Research Center of Pediatric Development (FRCPD) database from January 1, 2016 to December 31, 2021.

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Adenovirus pneumonia is a prevalent form of community-acquired pneumonia among children. Research on the epidemiology and economic burden of this disease is crucial for public health, yet comprehensive data remains scarce, making it crucial to highlight on this topic. In this study, the data were extracted from the face sheet of discharge medical records collected from 26 tertiary children's hospitals from January 2016 to December 2021.

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Importance: Adenovirus encephalitis is a significant infectious disease of the central nervous system that commonly affects children under the age of 5 and has a profound impact on the health of infants and young children throughout China. National multicenter epidemiological studies have significant public health implications.

Objective: This study aims to report the epidemiology of adenovirus encephalitis in hospitalized children in China, providing valuable guidance for clinicians.

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Article Synopsis
  • Congenital muscular torticollis (CMT) is a common condition in infants that can lead to limited neck movement and abnormal postures if not treated promptly.
  • A study analyzed treatment outcomes for 2,599 children with CMT, categorizing them into different groups based on the type of treatment they received, including physiotherapy and surgery.
  • Three CMT types were identified via ultrasound, allowing the researchers to compare treatment effectiveness and assess various clinical data related to the patients treated at Shenzhen Children's Hospital and other facilities in China.
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Background: In the past 20 years, an increasing number of studies have advanced our understanding of the pathogenic mechanism of chronic urticaria (CU), providing new treatment options.

Objectives: This bibliometric study aimed to evaluate published reports of CU-related studies from a number of different angles, review the research trends of the studies, and provide future perspectives of CU.

Materials & Methods: Publications related to CU from 2001-2022 were searched in the Web of Science Core Collection.

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Introduction: The therapeutic efficacy of systemic Janus kinase (JAK) inhibitors in moderate-to-severe atopic dermatitis (AD) is well established. However, the associated risk of incident acne, which is a prevalent adverse event in AD patients treated with systemic JAK inhibitors, has yet to be systematically analyzed.

Methodology: To evaluate the risk of incident acne in AD patients treated with systemic JAK inhibitors, an extensive database search (clinicaltrials.

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Objectives: Hypertension in children has attracted increasing attention. However, clinical-based studies investigating characteristics and secular trends of pediatric hypertension remain limited. This study aimed to investigate the clinical characteristics and secular trends of different types of hypertension among hospitalized children in China.

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Background: Recently, dupilumab has been used for the treatment of atopic dermatitis (AD), and growing interest in the subject has resulted in an increasing number of publications.

Objectives: Our study aimed to evaluate the rapid progress, identify hot topics, and explore scientific advances and future trends in this field.

Materials & Methods: The global distribution of publications was estimated with no time restrictions.

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Background: Epidemiological characteristics of paediatric burn can help to protect children from burn injuries. Most of the previous studies have been conducted on small scale and single centre in China. This study analysed the epidemiological characteristics of paediatric burn using a large-scale and multicentre database from 23 children's hospitals in China to increase child protection against burn injuries, improve the quality of care and reduce hospitalisation costs.

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Background: Dupilumab is the first approved IL-4Rα inhibitor for the treatment of atopic dermatitis at present with good efficacy and safety. However, there have been several reports of psoriasis and psoriasiform manifestations occurring after dupilumab therapy in recent years, showing a new paradoxical cutaneous reaction associated with biologics.

Summary: This is a scoping review in order to summarize the demographics and epidemiology, clinical manifestations, diagnosis, potential pathogenesis, and promising management of dupilumab-associated psoriasis and psoriasiform manifestations.

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Article Synopsis
  • * The most prevalent skin diseases identified were eczema and Paget's disease (PD), with a significant number of cases experiencing discrepancies between clinical and pathological diagnoses, particularly with adenoma of the nipple (AN).
  • * Key characteristics noted for PD include late onset and unilateral involvement, distinguishing it from eczema; the findings highlight the importance of understanding these conditions for accurate diagnosis.
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Atopic dermatitis (AD), a chronic inflammatory skin disorder characterized by recurrent eczema and intense pruritus, is a major skin-related burden worldwide. The diagnosis and treatment of AD is often challenging due to the high heterogeneity of AD, and its exact etiology is unknown. Metabolomics offers the opportunity to follow continuous physiological and pathological changes in individuals, which allows accurate diagnosis and management as well as providing deep insights into the etiopathogenesis of AD.

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Background: Bronchiolitis is a common acute lower respiratory tract infection (ALRTI) and the most frequent cause of hospitalization of infants and young children with ALRTI. Respiratory syncytial virus is the main pathogen that leads to severe bronchiolitis. The disease burden is relatively high.

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Background: Atopic dermatitis (AD) is the leading cause of skin-related disease burden worldwide, affecting a large percentage of the population. Bibliometrics is the statistical analysis of academic literature in a certain field.

Objectives: We aimed to perform the latest bibliometric analysis of atopic dermatitis literature.

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Background: Viral central nervous system (CNS) infections seriously threaten the life and health of children, with a high mortality and severe sequelae in China and globally. Surveillance of viral CNS infections in children is important, especially in hospitalized children, to facilitate disease evaluation.

Methods: In this study, we collected the data on the discharged Face Sheet of Medical Records from database from 2016 to 2020 and analyzed the epidemiologic characteristics and disease burden of hospitalized children (≤18 years old) with viral CNS infections in China.

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Background: Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Dupilumab, a monoclonal antibody that targets the interleukin (IL)-4 and IL-13 receptors, has been widely used in AD because of its efficacy. However, metabolic changes occurring in patients with AD in response to dupilumab remains unknown.

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