Rapid Separation of Representative Monomer Compound Rutin From Natural Product by Molecularly Imprinted Macroporous Adsorption Resin.

Monomer compounds from natural products are the major source of active pharmaceutical molecules, which provide great opportunities for discovering of new drugs. However, natural products contain a large number of rather complex compounds. It is difficult to obtain high-purity monomer compounds from complex natural products.

Research on Safety of Aero-Engine Oil Pipe Under Heating Conditions Based on Fluid-Solid Thermal Coupling.

This paper examines the safety of aero-engine pipelines under different heating conditions. Based on the fire test standard documents, a model of an aero-engine oil pipe was constructed, and its safety under heating conditions that meet the standard was analyzed using fluid-solid thermal coupling. The pipe material was stainless steel 1Cr18Ni9Ti, and the oil inside the pipeline was China RP-3 kerosene.

A novel tetrahedral framework nucleic acid-derived chemodynamic therapy agent for effective glioblastoma treatment.

Chemodynamic therapy (CDT) has garnered significant attention for treating diverse malignant tumours due to its minimally invasive nature, reduced damage to healthy tissues, and potential mitigation of side effects. However, its application in glioblastoma (GBM) is hindered by the diminished capacity of CDT agents to traverse the blood-brain barrier (BBB), inadequate tumour targeting efficiency, and restricted availability of HO within the tumour microenvironment (TME). To address these challenges, we devised a novel CDT agent (Fe@tFNAs-ANG-3AT) based on a tetrahedral framework nucleic acids (tFNAs).

Visualizing cancer resistance via nano-quenching and recovery detector of CD44.

Drug resistance to chemotherapy in cancers remains significant clinical challenges. CD44 modulates cellular adhesion, migration and growth, which plays a pivotal role in driving cancer resistance and even recurrence. Despite ongoing efforts, accurate, safe, and real-time dynamic monitoring techniques for CD44 expression remain inadequate in guiding the management of drug-resistant cancer treatment.

Adsorption Properties of Dissolved Gas Molecules in Transformer Oil on the ReSe Monolayer: A DFT Study.

Based on density functional theory, the adsorption behavior of seven typical dissolved gas molecules (CO, CO, H, CH, CH, CH, and CH) and HO molecule on the ReSe monolayer was systematically investigated. The interactions between the ReSe monolayer and eight gas molecules were investigated by calculating the adsorption energies, charge transfer, density of states (DOS), and deformation charge density (DCD) for eight different adsorption systems. The gas sensitivity of the ReSe monolayer toward these gases was studied using frontier molecular orbital theory and work function analysis.

Ag-Doped MoSe/ZnO Heterojunctions: A Highly Responsive Gas-Sensitive Material for Selective Detection of NO Based on DFT Study.

In this work, the adsorption and sensing behavior of Ag-doped MoSe/ZnO heterojunctions for H, CH, CO, NO, CO, and CH have been studied based on density functional theory (DFT). In gas adsorption analysis, the adsorption energy, adsorption distance, transfer charge, total electron density, density of states (DOS), energy band structure, frontier molecular orbital, and work function (WF) of each gas has been calculated. Furthermore, the reusability and stability of the Ag-doped MoSe/ZnO heterojunctions have also been studied.

Diagnostic role of heart rate variability in breast cancer and its relationship with peripheral serum carcinoembryonic antigen.

Objective: To investigate the diagnostic role of heart rate variability in breast cancer and its relationship with Carcinoembryonic antigen (CEA) in peripheral serum.

Methods: We reviewed the electronic medical records of patients who attended Zhujiang Hospital of Southern Medical University between October 2016 and May 2019. The patients were grouped based on breast cancer history and were divided into two groups: breast cancer group(n = 19) and control group(n = 18).