Publications by authors named "Yueli Fan"

Background: There is a growing focus on using various plant-derived agricultural by-products to increase the benefits of pig farming, but these feedstuffs are fibrous in nature. This study investigated the relationship between dietary fiber physicochemical properties and feedstuff fermentation characteristics and their effects on nutrient utilization, energy metabolism, and gut microbiota in growing pigs.

Methods: Thirty-six growing barrows (47.

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Article Synopsis
  • Eleutheroside E (EE) has immunocompetence, antioxidant, and anti-inflammatory properties, which were tested in porcine intestinal epithelial cells under LPS-induced stress.
  • Experimental groups included a control (C), a group treated with EE (E), one treated with LPS (L), and a combination (EL) of EE followed by LPS.
  • Results showed that EE promoted cell proliferation, reduced permeability, increased anti-inflammatory cytokines, and enhanced tight junction protein expression, while LPS negatively impacted the cells, highlighting EE's protective role against inflammation and permeability issues.
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Soybean agglutinin (SBA) is an anti-nutritional factor which decreases the mechanical barrier function in intestinal porcine jejunum epithelial cells (IPEC-J2). Eleutheroside E (EE) is a key part of Acanthopanax senticosus to exert pharmacological effects. This study aims to investigate the effects of EE on the barrier function in IPEC-J2 cells and to determine the ability of EE to enhance the protective effect of barrier function against SBA exposure.

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Eleutheroside B (EB) is a phenylpropanoid glycoside with anti-inflammatory properties, neuroprotective abilities, immunomodulatory effects, antinociceptive effects, and regulation of blood glucose. The aim of this study was to investigate the effects of EB on the barrier function in the intestinal porcine epithelial cells J2 (IPEC-J2). The IPEC-J2 cells were inoculated into 96-well plates at a density of 5 × 10 cells per well for 100% confluence.

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