Publications by authors named "Yuejuan Wu"
Purpose: This article aims to explore the relationship between the symptoms of PMS and changes of thalamic subregions.
Methods And Materials: 71 patients diagnosed with PMS and 81 healthy controls (HCs) were included in the study. Participant status was determined using the Daily Record of Severity of Problems (DRSP) scale.
Article Synopsis
- Women with premenstrual syndrome (PMS) are more likely to experience depression, potentially due to changes in white matter (WM) microstructure and inflammatory cytokine levels.
- The study aimed to assess WM alterations using diffusion tensor imaging (DTI) and measure inflammatory cytokine levels in PMS patients compared to healthy controls, while examining the relationship between these factors and the severity of PMS symptoms.
- Results showed PMS patients had lower fractional anisotropy (FA) and higher mean diffusivity (MD), along with elevated levels of inflammatory cytokines IL-1β and TNF-α, with significant correlations found between these metrics and symptom severity.
Aims: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). The disease mechanisms driving progressive MS remain unresolved. Without this information, current therapeutic strategies are unsatisfactory in preventing disease progression.
View Article and Find Full Text PDFHippocampal neuronal death plays a causal role in the cognitive impairment of temporal lobe epilepsy (TLE). Ferroptosis, a novel form of regulated cell death, is strongly linked to cognitive impairment. However, whether ferroptosis is associated with cognitive comorbidities of TLE is unknown.
View Article and Find Full Text PDFAutoimmune encephalitis (AE) is one kind of encephalitis that associates with specific neuronal antigens. Most patients with AE likely suffer from seizures, but data on the characteristics of seizure and antiepileptic drugs (AEDs) utilization in this patient group remains limited. This study aimed to report the clinical status of seizure and AEDs treatment of patients with AE, and to evaluate the relationship between AEDs discontinuation and seizure outcomes.
View Article and Find Full Text PDFMultiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Microglia are the resident innate immune cells in the CNS; they play an important role in the processes of demyelination and remyelination in MS. Microglia can function as antigen-presenting cells and phagocytes.
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