Bioinformatic analysis of CHEK1 as a marker of glomerular epithelial cell injury in diabetic nephropathy.

Diabetic nephropathy (DN) is considered to be a kidney disease caused by diabetes. In recent years, the incidence of DN has been on the rise, which is also a major challenge in the treatment and prognosis of the disease. Therefore, the search for new biomarkers of DN is urgent and has important clinical significance for reducing the morbidity and mortality of DN.

Hydraulic expansion facilitates remodeling of arteriovenous fistulas without increasing venous intimal hyperplasia in rabbits.

Background: An arteriovenous fistula (AVF) is considered essential for chronic hemodialysis.

Objective: To determine the effects of hydraulic expansion on the intimal hyperplasia of an AVF.

Methods: We divided 12 healthy male New Zealand white rabbits into a control group (vein without special handling and direct anastomosis with an artery, n = 6) and a hydraulic expansion group (vein dilated by hydraulic pressure before anastomosis, n = 6).

Maleic Anhydride-Grafted Isotactic Polybutene-1 and Modified Polyamide 6.

Maleic anhydride (MAH)⁻divinyl benzene (DVB) multi-monomer melt-grafting onto isotactic polybutene-1 (iPB-1) was carried out in a torque rheometer. The effects of dicumyl peroxide (DCP), MAH, and DVB concentrations, and temperature, on the reaction, were investigated. The optimized conditions were 170 °C, DVB/MAH = 4:6 (mass ratio).

Effect of Hydraulic Expansion on Arteriovenous Fistula of Hemodialysis Patients.

Background: Chronic kidney disease has become a serious public health problem in China. Our study is to explore effect of hydraulic expansion on arteriovenous fistula (AVF) of hemodialysis patients.

Methods: A total of 190 patients with end-stage renal disease (ESRD) were randomly divided into hydraulic expansion group ( = 117) and conventional surgery group ( = 73).

Early use of autogenous arteriovenous fistula in patients with urgent hemodialysis.

Purpose: This study was designed to evaluate the long-term patency rate and complications associated with early use of the autogenous forearm arteriovenous fistula (AFAVF) in patients needing urgent hemodialysis.

Methods: The clinical data of all patients undergoing AFAVFs for hemodialysis access between June 1996 and June 2016 were retrospectively evaluated. The primary and secondary patencies were estimated using the life table method.