Club cell secretory protein 16 is a potential biomarker for silica-induced pulmonary fibrosis.

This study was conducted to investigate the changes of Club cell protein 16 (CC16) and surfactant protein D (SP-D) levels in serum and bronchoalveolar lavage fluid (BALF) in silicotic rats and to explore their potential as early biomarkers for silicosis. Pulmonary fibrosis models of rats were constructed by exposing them to silica particles. BALF and serum were collected to determine CC16 and SP-D levels using enzyme-linked immunosorbent assay (ELISA) at different times after the exposure.

Detection of Pyrethroids in Food by Immunofluorescence Enhanced Method Based on Three-Layer Core-Shell Structure Upconversion Materials.

A novel rare earth upconversion nanomaterial with a three-layer sandwich core-shell structure was synthesized by an improved thermal decomposition method, and the morphology, fluorescence intensity and diffraction peak position of the new material were characterized by TEM (transmission electron microscope), XRD (Powder X-ray diffraction)and fluorescence spectrophotometer. The inert core/active shell/inert shell design improved the upconversion luminous efficiency of the new material several times. FTIR (Fourier transform infrared spectroscopy)characterization showed that the surface of activated upconversion nanoparticles was modified with silicon shell and amino group.