Cell cycle-regulated transcription factor AP2XII-9 is a key activator for asexual division and apicoplast inheritance in tachyzoite.

Unlabelled: is an intracellular parasitic protozoan that poses a significant risk to the fetus carried by a pregnant woman or to immunocompromised individuals. tachyzoites duplicate rapidly in host cells during acute infection through endodyogeny. This highly regulated division process is accompanied by complex gene regulation networks.

AP2XII-1 and AP2XI-2 Suppress Schizogony Gene Expression in .

is an intracellular parasite that is important in medicine and veterinary science and undergoes distinct developmental transitions in its intermediate and definitive hosts. The switch between stages of is meticulously regulated by a variety of factors. Previous studies have explored the role of the microrchidia (MORC) protein complex as a transcriptional suppressor of sexual commitment.

Mitochondrial dysfunction induced by bedaquiline as an anti-Toxoplasma alternative.

Toxoplasma gondii is a zoonotic parasite that infects one-third of the world's population and nearly all warm-blooded animals. Due to the complexity of T. gondii's life cycle, available treatment options have limited efficacy.

Controls and variability of soil respiration temperature sensitivity across China.

Understanding the temperature sensitivity (Q) of soil respiration is critical for benchmarking the potential intensity of regional and global terrestrial soil carbon fluxes-climate feedbacks. Although field observations have demonstrated the strong spatial heterogeneity of Q, a significant knowledge gap still exists regarding to the factors driving spatial and temporal variabilities of Q at regional scales. Therefore, we used a machine learning approach to predict Q from 1994 to 2016 with a spatial resolution of 1 km across China from 515 field observations at 5 cm soil depth using climate, soil and vegetation variables.

Evaluation of the Combined Effect of Artemisinin and Ferroptosis Inducer RSL3 against .

is a widespread intracellular pathogen that infects humans and a variety of animals. Dihydroartemisinin (DHA), an effective anti-malarial drug, has potential anti- activity that induces ferroptosis in tumor cells, but the mechanism by which it kills is not fully understood. In this study, the mechanism of DHA inhibiting growth and its possible drug combinations are described.

The anti- activity of the plant natural phenolic compound piceatannol.

is an obligate intracellular protozoan that infects the nucleated cells of warm-blooded animals and causes life-threatening disease in immunocompromised patients. Due to the limited effectiveness and prominent side effects of existing drugs, there is an urgent need to develop new therapeutic options against . Piceatannol is a natural plant compound with multiple functions such as antibacterial, antileukemic and antiparasitic activities.

A decreasing carbon allocation to belowground autotrophic respiration in global forest ecosystems.

Belowground autotrophic respiration (RA) depends on carbohydrates from photosynthesis flowing to roots and rhizospheres, and is one of the most important but least understood components in forest carbon cycling. Carbon allocation plays an important role in forest carbon cycling and reflects forest adaptation to changing environmental conditions. However, carbon allocation to RA has not been fully examined at the global scale.

[Allelopathic effects of secalonic acid F produced by Aspergillus japonicus on Zea mays].

Aspergillus japonicus Saito is a common soil-borne fungus, and exists on the surface of some cereal crop seeds. Secalonic acid F (SAF) is the main allelochemical from the fungus. Bioassays showed that SAF significantly stimulated the seedling growth of corn (Zea mays L.