The Construction and Mechanism Study of High-Speed Carrier Transport Channel in Gallium Arsenide Homojunction Toward High-Performance Photoelectrochemical Photodetector.

The energy band structure and surface/interface properties are prerequisite for not only preserving the intrinsic material quality but also manipulating carrier transport behavior for photoelectrochemical (PEC) photodetection. How to precisely design/regulate the band structure and surface/interface properties of semiconductor materials is the key to improving the performance of PEC photodetection. Herein, the quintuple heterotypic homojunction (QH) GaAs film is fabricated with a gradient energy band via plasma-assisted molecular beam epitaxy for constructing a high-speed carrier transport channel in PEC photodetection, which can efficiently drive the separation and transport of photogenerated electron-hole pairs.

Active Passivation of Anion Vacancies in Antimony Selenide Film for Efficient Solar Cells.

Binary antimony selenide (SbSe) is a promising inorganic light-harvesting material with high stability, nontoxicity, and wide light harvesting capability. In this photovoltaic material, it has been recognized that deep energy level defects with large carrier capture cross section, such as V (selenium vacancy), lead to serious open-circuit voltage (V) deficit and in turn limit the achievable power conversion efficiency (PCE) of SbSe solar cells. Understanding the nature of deep-level defects and establishing effective method to eliminate the defects are vital to improving V.

Effect of Energy-driven Molecular Precursor Decomposition on the Crystal Orientation of Antimony Selenide Film and Solar Cell Efficiency.

Antimony selenide (SbSe) consists of 1D (SbSe) ribbons, along which the carriers exhibit high transport efficiency. By adjusting the deposition parameters of vacuum-deposited methods, such as evaporation temperature, chamber pressure, and vapor concentration, it is possible to grow the (SbSe) ribbons vertically or highly inclined towards the substrate, resulting in films with [hk1] orientation. However, the specific mechanisms by which these deposition parameters affect the orientation of thin films require a deeper understanding.

Combinatorial metabolic engineering of for improved production of 7-dehydrocholesterol.

7-Dehydrocholesterol (7-DHC), a key pharmaceutical intermediate in the production of vitamin D, has a wide range of applications. To explore fermentative synthesis of 7-DHC, a 7-DHC-producing strain was constructed by blocking the competitive pathway, eliminating rate-limiting steps, altering global regulation, and pathway compartmentalization. After blocking the competitive pathway by disrupting and and introducing from produced 139.

Recent advances in construction and regulation of yeast cell factories.

The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products in the last 5 years, this review introduces different yeast chassis used for cell factory construction, including Saccharomyces cerevisiae, Yarrowia lipolytica and Komagataella phaffii, together with the emerging genome editing tools. The metabolic regulation strategies developed for yeast engineering are highlighted, such as subcellular pathway localization dynamic regulation, and transporter engineering.

Metabolic engineering strategies for de novo biosynthesis of sterols and steroids in yeast.

Steroidal compounds are of great interest in the pharmaceutical field, with steroidal drugs as the second largest category of medicine in the world. Advances in synthetic biology and metabolic engineering have enabled de novo biosynthesis of sterols and steroids in yeast, which is a green and safe production route for these valuable steroidal compounds. In this review, we summarize the metabolic engineering strategies developed and employed for improving the de novo biosynthesis of sterols and steroids in yeast based on the regulation mechanisms, and introduce the recent progresses in de novo synthesis of some typical sterols and steroids in yeast.

Characterization of a recombinant sucrose isomerase and its application to enzymatic production of isomaltulose.

Objective: To characterize a recombinant isomerase that can catalyze the isomerization of sucrose into isomaltulose and investigate its application for the enzymatic production of isomaltulose.

Results: A sucrose isomerase gene from Erwinia sp. Ejp617 was synthesized and expressed in Escherichia coli BL21(DE3).