Publications by authors named "Yuehang Zhang"
Article Synopsis
- A study involving 1,915 peritoneal dialysis patients in China aimed to examine the link between time spent within the target range of serum phosphorus levels and mortality risk.
- The research found that longer durations with serum phosphorus levels between 1.13-1.78 mmol/L were associated with lower rates of all-cause and cardiovascular mortality, as well as decreased withdrawal from dialysis treatment.
- These results emphasize the importance of maintaining appropriate serum phosphorus levels to potentially improve survival outcomes for patients on peritoneal dialysis.
renal tissue engineering is promising yet challenging for renal injury repair and regeneration due to the highly vascularized structure of renal tissue and complex high-oxidative stress and ischemic microenvironment. Herein, a novel biocompatible 3D porous hydrogel (DFO-gel) with sustained release capacity of hypoxia mimicking micromolecule drug deferoxamine (DFO) was developed for renal injury repair. and experimental results demonstrated that the developed DFO-gels can exert the synchronous benefit of scavenging excess reactive oxygen species (ROS) regulating inflammatory microenvironment and promoting angiogenesis for effective renal injury repair by up-regulating hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF).
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