A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(i).

The disruption of copper homeostasis (Cu/Cu) may cause neurodegenerative disorders. Thus, the need for understanding the role of Cu in physiological and pathological processes prompted the development of improved methods of Cu analysis. Herein, a new near-infrared (NIR) fluorescent turn-on probe (NPCu) for the detection of Cu was developed based on a Cu-mediated benzylic ether bond cleavage mechanism.

A novel dual-function fluorescent probe for the rapid detection of bisulfite and hydrogen peroxide in aqueous solution and living cells.

In this work, Hcy-OB, a novel hemicyanine-based biocompatible dual-function fluorescence probe for bisulfite and HO detection is designed and synthesized. Based on a 1,4-addition reaction, Hcy-OB can be used for bisulfite detection with fast response, high sensitivity and low detection limit (120 nM). In addition, the probe is successfully applied to the detection of bisulfite in aqueous solution.

An effective biocompatible fluorescent probe for bisulfite detection in aqueous solution, living cells, and mice.

Sulfur dioxide, an air pollutant, is easily hydrated to sulfites and bisulfites and extremely harmful to human health. On the other hand, endogenous sulfur dioxide is the fourth gasotransmitter. In view of the above, it is worth developing an effective method for the detection of these compounds.