Adrenomedullin 2 attenuates anxiety-like behaviors by increasing IGF-II in amygdala and re-establishing blood-brain barrier.

Anxiety disorder, a prevalent mental health issue, is one of the leading causes of disability worldwide. Damage to the blood-brain barrier (BBB) is implicated in anxiety, but its regulatory mechanisms remain unclear. Herein, we show that adrenomedullin 2 (ADM2), a novel angiogenic growth factor, alleviates autistic and anxiety-like behaviors in mice.

Fine mapping of a novel QTL for fruit skin gloss in cucumber ( L.).

Unlabelled: Cucumber ( L.) is an important vegetable crop that is popular with many people. Peel gloss is a highly valued external quality trait that affects the market value of cucumbers, and it directly influences the purchasing psychology of consumers.

A high-continuity and annotated tomato reference genome.

Background: Genetic and functional genomics studies require a high-quality genome assembly. Tomato (Solanum lycopersicum), an important horticultural crop, is an ideal model species for the study of fruit development.

Results: Here, we assembled an updated reference genome of S.

Seed-mediated synthesis and characterization of Ni flower-like nanomaterials.

Flower-like Ni nanoparticles in diameter of 200 approximately 250 nm were synthesized by a mild chemical solution method. They were composed of smaller single-crystal Ni grains with an average diameter of approximately 15 nm. XRD, EDS and HRTEM results show that these particles were mixed uniformly with iron oxide single crystals, which serve as seeds for the growth of the flower-like structure.