Publications by authors named "YueNan Huang"
Article Synopsis
- Cancer survivors in China are more at risk for severe influenza complications but face significant vaccine hesitancy, with 42.06% of a surveyed group reporting they were hesitant to get vaccinated.
- The study collected data from 500 cancer survivors through questionnaires, revealing that factors such as time since treatment, family support, and information from healthcare providers greatly influence vaccine hesitancy.
- To improve vaccination rates in this at-risk group, it's essential to address vaccine safety concerns, enhance communication between patients and doctors, and expand access to vaccination resources.
The immunonutritional status has important effects on outcomes for cancer patients. Albumin-to-globulin ratio (AGR) and the prognostic nutrition index (PNI) are often used to assess the immunonutritional status of cancer patients. However, the clinical significance of these factors in colorectal cancer (CRC) remains unclear.
View Article and Find Full Text PDFInflammatory bowel disease (IBD) is a chronic non-specific inflammatory disease that occurs in the intestinal tract. It is mainly divided into two subtypes, i.e.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the clinical significance of the preoperative pan-immune-inflammation value (PIV) in patients with colorectal cancer (CRC).
- Involving 366 patients, the research analyzed factors such as tumor size and specific biomarkers to understand the PIV's correlation with clinicopathological features of CRC.
- Results indicated that PIV is positively related to tumor size and certain cancer markers, suggesting it could be an important tool for preoperative assessment of CRC stages.
Circular RNAs (circRNAs) are regarded as a novel class of widespread endogenous non-coding RNAs, which may play important roles in tumorigenesis by regulating gene expression. Nevertheless, the characterization of circRNAs in epithelial ovarian cancer (EOC) remains largely unknown. This study aimed to investigate circRNA expression profiles in EOC.
View Article and Find Full Text PDFPrevious studies evaluating the association between smoking and risk of cholangiocarcinoma (CCA) have yielded controversial results. We conducted a meta-analysis to evaluate the association based on available evidence. We searched the databases of Embase, PubMed and Cochrane Central Register of Controlled Trials from inception to April 11, 2017.
View Article and Find Full Text PDFPurpose: To investigate the association of cancer stem-cell markers [octamer-binding transcription factor 4 (OCT4), sex determining region Y-box 2 (SOX2), and Nanog homebox (NANOG)] expression with clinicopathological properties and overall survival (OS) in operative rectal cancer (RC) patients receiving adjuvant therapy.
Materials And Methods: 153 patients with primary RC receiving surgery were enrolled. Tumor tissue and paired adjacent normal tissue sample were collected, and OCT4, SOX2, and NANOG expressions were assessed by immunofluorescent staining.
Colorectal cancer (CRC) is one of the most common reasons for cancer-associated mortality worldwide. The present study aimed to investigate the drug resistance mechanism of the oxaliplatin (OXA)-resistant HT-29 cell line (HT-29/L-OHP) and examine the expression of lysosome-associated protein transmembrane 4β (LAPTM4β), a drug resistance-associated gene. In the present study, a drug concentration gradient method was used to establish the drug-resistant HT-29/L-OHP cell line.
View Article and Find Full Text PDFPrevious studies investigating the association between statin use and survival outcomes in gynecologic cancers have yielded controversial results. We conducted a systematic review and meta-analysis to evaluate the association based on available evidence. We searched the databases of the Cochrane Central Register of Controlled Trials (CENTRAL), Embase, and PubMed from inception to January 2017.
View Article and Find Full Text PDFAssociation between adiponectin polymorphisms and the risk of colorectal cancer.
Genet Test Mol Biomarkers
January 2015
Purpose: To discuss the association between adiponectin (ADIPOQ) gene rs2241766 and rs1501299 polymorphisms and the risk of colorectal cancer, and to analyze the role of the interaction between these two loci and environmental factors in colorectal cancer pathogenesis.
Methods: The case-control study was performed with a 1:1 match. A self-designed questionnaire was used to perform a face-to-face survey with 600 new primary colorectal cancer cases confirmed by histopathology as well as 600 cases of people receiving a physical examination at the same time.
Background: The purpose of this study was to determine whether lysosome-associated protein transmembrane-4 beta (LAPTM4B) overexpression is associated with the prognosis in patients with colorectal cancer.
Methods: LAPTM4B expression was evaluated in colorectal cancer patients by Western blot analysis and immunohistochemistry. Univariate and multivariate analyses were performed to determine the association between LAPTM4B expression and prognosis.