Publications by authors named "Yue-rong Wang"
Objective: Periodontitis is a progressive and inflammatory oral disease and results in the damage of the supporting tissues of teeth. Peroxiredoxin 6 (PRDX6) is an antioxidant enzyme identified as a regulator in ferroptosis. This study aimed to investigate whether PRDX6 could protect human gingival fibroblasts (HGFs) from lipopolysaccharide (LPS)-induced inflammation and its mechanisms.
View Article and Find Full Text PDFOral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid. Chemotherapeutic agents such as cisplatin, 5-fluorouracil, and paclitaxel have now become the first-line options for OSCC patients. Nevertheless, most OSCC patients eventually acquire drug resistance, leading to poor prognosis.
View Article and Find Full Text PDFArticle Synopsis
- Stroke and cerebral I/R injury can cause serious problems if not treated quickly.
- Scientists studied a type of RNA called circular RNAs (circRNAs) to see how they might affect brain injuries caused by a lack of blood flow.
- They found that one specific circRNA, circ-camk4, increased in brain cells after an injury and appeared to make the cells more likely to die, suggesting it plays an important role in brain damage after a stroke.
SIRT 1 binding with PKM and NSE and modulate their acetylation and activities.
Biochim Biophys Acta Proteins Proteom
September 2019
SIRT1 (Silent mating type information regulation 2 homolog 1) play a neuroprotective effect through deacetylation target proteins in various neuronal diseases. However, the precise mechanisms remain elusive. In this study, we aim to identify those novel interacting partners of SIRT1 in rat brain tissue.
View Article and Find Full Text PDF[Effect of Chuanhuang No. 1 recipe on renal function and micro-inflammation in phase 3 chronic kidney disease patients].
Zhongguo Zhong Xi Yi Jie He Za Zhi
February 2015
Article Synopsis
- The study aimed to assess the effectiveness of Chuanhuang No.1 Recipe (CHR) on kidney function and inflammation in patients with phase 3 chronic kidney disease (CKD) compared to Losartan Potassium.
- A total of 60 CKD patients were randomly divided into two groups, receiving either CHR or Losartan for 24 weeks, and various renal biomarkers were measured before and after treatment.
- Results showed that CHR led to significant improvements in serum creatinine, blood urea nitrogen, and overall kidney function, while also reducing inflammation markers more effectively than Losartan, resulting in a higher overall treatment success rate with CHR.