Publications by authors named "Yue-qiu Luo"
Article Synopsis
- This systematic review and meta-analysis examined the link between serum vitamin D levels and the severity of liver fibrosis in patients with chronic hepatitis C, analyzing data from approximately 8,321 participants across six studies.
- It found that lower serum vitamin D levels may be associated with increased severity of liver fibrosis, based on mean data from three studies, but not a consistent conclusion could be drawn from the odds ratio data from four other studies.
- Significant variability was noted among the studies, indicating that while there is a potential risk factor relationship between low vitamin D and liver fibrosis severity, the evidence is not definitive due to inconsistencies in the data.
[Establishment of a cell line with antisense-blocked POLH and the role of POLH in alkylating agent MNNG induced nontargeted mutagenesis].
Zhejiang Da Xue Xue Bao Yi Xue Ban
October 2003
Objective: To investigate the function of POLH(polymerase eta) through establishment of the POLH gene-blocked cell line FL-POLH(-).
Methods: A mammalian expression vector expressing antisense POLH gene fragment pMAMneo-amp-POLHA (-) was constructed by cloning the 1473 - 2131 fragment of POLH gene into the mammalian expression vector pMAMneo-amp(-) in antisense orientation. The FL cells were transfected with this antisense RNA expressing vector and selected by G418.