Publications by authors named "Yue-Yu Sun"
Article Synopsis
- - Mitochondrial diseases (MDs) are complex disorders caused by issues in both mitochondrial and nuclear DNA, and a study was conducted using dual genomic sequencing to improve diagnosis in pediatric patients.
- - In a review of 503 pediatric patients, causative genetic variants were found in 177 (35.2%), with a notable fraction (9.1%) having variants directly related to mitochondria.
- - Dual genomic sequencing proved effective for identifying mitochondrial disorders, but notably, some patients with mitochondrial-related variants were still misclassified as unlikely to have such disorders, highlighting the need for careful evaluation.
Idiopathic pulmonary hemosiderosis (IPH) is an extremely rare cause of massive pulmonary hemorrhage in children. During the acute phase, death due to massive alveolar hemorrhage and subsequent severe respiratory failure. We report two cases of IPH children who developed hypoxemic respiratory failure and massive pulmonary hemorrhage.
View Article and Find Full Text PDFBackground And Purpose: Early or primary application of high-frequency oscillatory ventilation (HFOV) has been recently suggested not to offer benefit to patients with acute respiratory distress syndrome (ARDS). However, the rescue effects of HFOV on severe pediatric acute respiratory distress syndrome (PARDS) with hypoxemia refractory to conventional mechanical ventilation (CMV) remain unclear. This study aimed to determine whether severe PARDS children would benefit from HFOV when oxygenation deteriorated on CMV and to identify any potential risk factors related to mortality.
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