Age-related hearing loss accelerates the decline in fast speech comprehension and the decompensation of cortical network connections.

Patients with age-related hearing loss face hearing difficulties in daily life. The causes of age-related hearing loss are complex and include changes in peripheral hearing, central processing, and cognitive-related abilities. Furthermore, the factors by which aging relates to hearing loss via changes in auditory processing ability are still unclear.

Tinnitus Abnormal Brain Region Detection Based on Dynamic Causal Modeling and Exponential Ranking.

Dynamic Causal Modeling (DCM) has been extended for the analysis of electroencephalography (EEG) based on a specific biophysical and neurobiological generative model for EEG. Comparing to methods that summarize neural activities with linear relationships, the generative model enables DCM to better describe how signals are generated and better reveal the underlying mechanism of the activities occurring in human brains. Since DCM provides us with an approach to the effective connectivity between brain areas, with exponential ranking, the abnormality of the observed signals can be further located to a specific brain region.

Brain Network Regional Synchrony Analysis in Deafness.

Deafness, the most common auditory disease, has greatly affected people for a long time. The major treatment for deafness is cochlear implantation (CI). However, till today, there is still a lack of objective and precise indicator serving as evaluation of the effectiveness of the cochlear implantation.