Publications by authors named "Yue-Wei Zhang"

Soil salinization poses a significant global challenge, exerting adverse effects on both agriculture and ecosystems. Planting halophytes has the potential ability to improve saline-alkali land and enhance ecosystem multifunctionality (EMF). However, it remains unclear which halophytes are effective in improving saline-alkali land and what impact they have on the rhizosphere microbial communities and EMF.

View Article and Find Full Text PDF

Hepatic artery infusion chemotherapy (HAIC) has good clinical efficacy in the treatment of advanced hepatocellular carcinoma (HCC); however, its efficacy varies. This review summarized the ability of various markers to predict the efficacy of HAIC and provided a reference for clinical applications. As of October 25, 2023, 51 articles have been retrieved based on keyword predictions and HAIC.

View Article and Find Full Text PDF
Article Synopsis
  • * HAIC using oxaliplatin, fluorouracil, and leucovorin (referred to as HAIC-FOLFOX) has shown better survival rates than standard first-line treatments, but inconsistencies in the HAIC procedure have led to challenges in its safe application.
  • * An expert consensus conference held in March 2023 in Guangzhou, China resulted in 22 recommendations that cover the candidate assessment, technical details, outcomes, complications, and management strategies related to HA
View Article and Find Full Text PDF

Background: Cavernous transformation of the portal vein (CTPV) due to portal vein obstruction is a rare vascular anomaly defined as the formation of multiple collateral vessels in the hepatic hilum. This study aimed to investigate the imaging features of intrahepatic portal vein in adult patients with CTPV and establish the relationship between the manifestations of intrahepatic portal vein and the progression of CTPV.

Methods: We retrospectively analyzed 14 CTPV patients in Beijing Tsinghua Changgung Hospital.

View Article and Find Full Text PDF

Background: Primary hepatocellular carcinoma is often complicated with hepatitis and liver cirrhosis. Some patients develop different degrees of splenomegaly, hypersplenism and hypohepatia due to the aggravation of liver cirrhosis, which to some extent interfere with the treatment of tumors and even affect the prognosis of patients. In this study, we prospectively evaluate the efficacy and safety of simultaneous CalliSpheres microspheres transcatheter arterial chemoembolization (CSM-TACE) and partial splenic embolization (PSE) using 8spheres for hepatocellular carcinoma (HCC) with hypersplenism.

View Article and Find Full Text PDF

In order to conduct in-depth research on the mechanisms of cancer diagnosis and treatment, it is very important to develop fluorescent probes to study the interactions between different organelles and understand the relationship between various organelles and cell viability. However, the lack of fluorescent probes to visualize two or more targets has resulted in limited studies of intracellular interactions between different organelles. To this end, in this work, we developed a near-infrared (NIR) AIE probe with dual-color emission, NAP-Py-E, for mitochondria and lipid droplets imaging.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to monitor early changes in blood cytokines after treating metastatic hepatic carcinoma using a specific method called CSM-TACE with drug-eluting beads.
  • Twenty-eight patients with treatment-resistant MHC underwent blood tests before and after CSM-TACE, assessing inflammatory factors and immune cell ratios using flow cytometry.
  • Results showed dynamic fluctuations in cytokine levels, indicating an acute inflammatory response alongside a boost in the body's anti-tumor immune response after the treatment.
View Article and Find Full Text PDF

Objective: To explore the clinical efficacy and prognostic factors of the use of Gelfoam for drug-eluting bead (DEB) transarterial chemoembolization (GMD-TACE) in patients with unresectable large hepatocellular carcinoma (HCC) and portal vein tumor thrombus (PVTT).

Methods: A retrospective analysis was conducted using the mRECIST standard to evaluate tumor response after GMD-TACE. Overall survival time, median survival time, time to progression (TTP) after the first intervention, and other treatment methods were recorded.

View Article and Find Full Text PDF

To assess the clinical efficacy and safety of gelatin sponge microparticles-transcatheter arterial chemoembolization (GSMs-TACE) plus synchronous antigen-presenting dendritic cell (DC) sequential reinfusion for advanced large liver cancer (LC).Patients with large LC were assigned to the experimental (combined sequential DC therapy) or control group. All patients received standardized GSMs-TACE.

View Article and Find Full Text PDF

Objective To explore the feasibility of using ultrasound to evaluate stent placement for managing graft stenosis after Meso-rex bypass for cavernous transformation of the portal vein in adults. Methods This study enrolled the patients who underwent Meso-rex bypass due to cavernous transformation of the portal vein,were diagnosed graft stenosis by postoperative ultrasound,and then underwent percutaneous portal vein puncture portography and stent placement.We then compared the ultrasonic measurement indicators and sonographic manifestations before and after stent placement,and evaluated the alleviation of portal hypertension symptoms after stent placement and related clinical indexes.

View Article and Find Full Text PDF

Surgical resection (SR) is recommended as a radical procedure in the treatment of hepatocellular carcinoma (HCC). However, postoperative recurrence negatively affects the long-term efficacy of SR, and preoperative adjuvant therapy has therefore become a research hotspot. Some clinicians adopt transcatheter arterial chemoembolization (TACE) as a preoperative adjuvant therapy in patients undergoing SR to increase the resection rate, reduce tumor recurrence, and improve the prognosis.

View Article and Find Full Text PDF

Objective: To retrospectively analyze the safety and long-term clinical efficacy of gelatin sponge microparticles combined with the chemotherapy drug pirarubicin for hepatic transcatheter arterial chemoembolization (GSMs-TACE) in order to treat breast cancer liver metastasis (BCLM).

Methods: Twenty-seven BCLM patients who underwent GSMs-TACE from July 2010 to July 2016 were enrolled. Tumor target blood vessels were slowly and regionally embolized with absorbable gelatin sponge particles and pirarubicin injections.

View Article and Find Full Text PDF

Background: To observe the medium- and long-term clinical efficacy and safety of radioactive I seed implantation for refractory malignant tumours based on CT-guided 3D template-assisted technique.

Methods: Twenty-five patients with refractory malignant tumours who underwent radioactive I seed implantation based on CT-guided 3D template-assisted technique were selected. The post-operative adverse reactions were recorded.

View Article and Find Full Text PDF

Ginsenoside-Rg5, which is derived from high temperature-processed ginseng, exhibits beneficial health effects. In the present study, ginsenoside-Rg5 was directly and rapidly prepared through the extraction of ginseng fibrous root powder (GFRP) at atmospheric pressure. The results showed that the highest extraction yield (3.

View Article and Find Full Text PDF

Background: Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for assessing both RAS and RMP to achieve a one-stop assessment of patients with suspected renovascular hypertension.

View Article and Find Full Text PDF

Purpose: We evaluated the clinical efficacy of gelatin sponge microparticle (GSM) -mediated chemoembolization for the treatment of patients with liver metastases following surgery for gastrointestinal tumors.

Materials And Methods: In a retrospective analysis of 37 patients who were treated at our hospital with GSM-mediated chemoembolization for liver metastases over 13 years, we evaluated outcomes using a modified response evaluation criteria in solid tumors system and also assessed liver function and adverse effects. All patients had previously undergone surgery for gastrointestinal tumors.

View Article and Find Full Text PDF

To evaluate the safety and efficacy of transarterial arterial chemoembolization (TACE) with gelatin sponge particles (GSPs-TACE) and Huaier granule to treat primary hepatic carcinoma (PHC).A series of 62 patients with PHC were included between June 2009 and December 2011, and randomly assigned to a control (n = 31) or an experimental group (n = 31). The control patients received TACE with 350 to 560 μm GSPs plus lobaplatin chemotherapy.

View Article and Find Full Text PDF

To retrospectively analyze the safety and efficacy of 350-560 μm gelatin sponge particles combined with single-chemotherapy drug transcatheter arterial chemoembolization (Gs-TACE) for the treatment of elderly hepatocellular carcinoma without surgical resection.Thirty elderly hepatocellular carcinoma patients without surgical resection, who received Gs-TACE in our hospital, were selected. Slowly injected gelatin sponge particles (350-560 μm)+ 10 mg lobaplatin injection into the regional embolization tumor target vessel.

View Article and Find Full Text PDF

Spontaneous rupture of hepatocellular carcinoma hemorrhage is life-threatening. The aim of the present study was to retrospectively analyze the effect of gelatin sponge microparticles (GSMs) of various diameters on the treatment of spontaneous rupture of hepatocellular carcinoma hemorrhage. GSMs serve as embolization agents by transcatheter arterial chemoembolization (TACE), and the current study analyzed their safety and efficacy.

View Article and Find Full Text PDF

Hyporheic macroinvertebrates are an important component of stream ecosystem. The composition and distribution of the hyporheic macroinvertebrates were investigated using artificial substrates in the upper reaches of Heishuitan River in August, December 2013 and April 2014. The results indicated that a total of 27 microinvertbrate species were identified in all three seasons.

View Article and Find Full Text PDF

Gelatin sponge particles are commonly used in the conventional transarterial chemoembolization (c-TACE) as an adjuvant embolizing agent for hepatocellular carcinoma (HCC). However, there are few reports regarding the clinical applications of gelatin sponge microparticles (GSMs) as a main embolizing agent in the treatment of HCC. This retrospective study aim to evaluate the efficacy and safety of patients with Barcelona Clinic Liver Cancer (BCLC) stage B HCC treated with intra-arterial injection of 350 to 560 μm GSMs mixed with anticancer agents.

View Article and Find Full Text PDF

The pothole is one of the special habitats in river ecosystems, which is simply structured, well-defined, food chain-short, and easily controlled, thus making it a model system in ecological, evolutionary and phenological studies. Here we first reviewed hydrological, chemical and physical characteristics of potholes, their biological community (biodiversity, environmental factors) as well as food chain (competition, predation and parasitism) in mountain rivers. The differences between pothole ecosystems and river ecosystems in hydrological characteristics, biological community and food-chain were analyzed.

View Article and Find Full Text PDF

The stream hyporheic zone is an ecotone of surface water-ground water interactions, which is rich in biodiversity, and is an important component of stream ecosystem. The macroinvertebrates, which are at the top of food webs in the hyporheic zone to directly influence the matter and energy dynamics of the hyporheic zone, and are potential indicators of river ecological health to adjust the function of environment purification and ecological buffer. The macroinvertebrates in the hyporheic zone are divided into three categories: stygoxenes, stygophiles and stygobites.

View Article and Find Full Text PDF

The objective of this study is to investigate pharmacokinetics of gelatin sponge microparticles (GSMs) combined with epirubicin in a rabbit VX2 liver tumor model of hepatic arterial chemoembolization (TACE). Eighteen successful models of VX2 in New Zealand white rabbits was established, which were divided into three groups randomly: HAI group (n = 6), the epirubicin solution (epirubicin 10 mg mixed with saline 10 ml into the hepatic artery); GSMs-TACE group (n = 6), GSMs (20 mg) mixed with epirubicin solution (1 mg/ml); c-TACE group (n = 6), epirubicin (10 mg) mixed with lipiodol (10 ml). Each rabbit was administrated epirubicin at dose adjusted for a 1 mg/kg.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Yue-Wei Zhang"

  • - Yue-wei Zhang's recent research predominantly focuses on the application of various medical therapies for hepatocellular carcinoma (HCC), particularly emphasizing the efficacy and safety of transcatheter arterial chemoembolization (TACE) techniques using gelatin sponge microparticles and other agents in treating advanced liver cancer.
  • - Zhang's studies also explore the ecological aspects of soil salinization and the potential of halophytes in improving ecosystem multifunctionality, thereby addressing significant environmental challenges while enhancing agricultural productivity.
  • - The author's work includes the development of diagnostic techniques and imaging features, aiming to improve patient outcomes through better prognostic evaluations and treatment strategies for hepatic arterial infusion chemotherapy, as well as classifications for vascular anomalies related to liver disease.