Publications by authors named "Yue-Jun Xiao"
Med Sci Monit
January 2019
Article Synopsis
- Periprosthetic osteolysis, a common issue after joint replacement surgeries, is caused by wear particles and inflammation affecting macrophages.
- This study explored the effects of curcumin, a natural compound, on macrophages exposed to polyethylene particles, using both lab tests on isolated macrophages and a mouse model.
- Results showed that curcumin not only promotes cholesterol efflux in macrophages and helps maintain a non-inflammatory state but also leads to better bone density and reduced inflammation in the treated mice.
