2,4-dichlorophenol(2,4-DCP), a highly toxic and refractory organic compound, was commonly used in pesticide production and thus widely distributed in water and soil. Goethite, magnetite and gypsum were added into the anaerobic system which simulated the natural anaerobic process to evaluate their effects on the anaerobic degradation of 2,4-DCP. It indicated that goethite, magnetite and gypsum had no appreciable adsorption ability toward 2,4-DCP under anaerobic condition.
View Article and Find Full Text PDFBiological treatment played an important role in the treatment of landfill leachate. In the current study, acid mine drainage (AMD) was used as a source of sulfate to strengthen the anaerobic treatment of landfill leachate. Effects of chemical oxygen demand (COD) and SO mass concentration ratio on the decomposition of organic matter, methane production and sulfate reduction were investigated and the microbial community was analyzed using the high throughout methods.
View Article and Find Full Text PDFSearching for effective pharmacological agents for traumatic brain injury (TBI) treatment has largely been unsuccessful. The transient receptor potential melastatin 7 (TRPM7), a TRP channel that is essential for embryonic development, has been shown to mediate ischemic neuronal injury in vivo and in vitro, but global deletion of TRPM7 in mice is lethal. Here, carvacrol was used to investigate the protective effect of TRPM7 inhibition in an in vitro traumatic neuronal injury model.
View Article and Find Full Text PDFBackground: Drug combination therapies using cisplatin and natural products are common practice in the treatment of human lung cancer. Osthole is a natural compound extracted from a number of medicinal plants and has been shown to exert strong anticancer activities with low toxicity.
Methods: In the present study, NBM-T-BMX-OS01 (BMX), derived from the semi-synthesis of osthole, was evaluated in cisplatin treated A549 cells to investigate its effect on cisplatin resistance in human lung cancer.
Competitive adsorption of heavy metals by extracellular polymeric substances (EPS) extracted from Desulfovibrio desulfuricans was investigated. Chemical analysis showed that different EPS compositions had different capacities for the adsorption of heavy metals which was investigated using Cu(2+) and Zn(2+). Batch adsorption tests indicated that EPS had a higher combined ability with Zn(2+) than Cu(2+).
View Article and Find Full Text PDFA large part of groundwater in the Chinese Loess Plateau area is characterized by high arsenic concentration. Anaerobic bacteria have been considered to play key roles in promoting arsenic releasing from loess to groundwater. However, this hypothesis remains unconfirmed.
View Article and Find Full Text PDFSynthetic effect between sulfate minerals (gypsum) and iron oxide (hematite) on the anaerobic transformation of organic substance was investigated in the current study. The results showed that gypsum was completely decomposed while hematite was partially reduced. The mineral phase analysis results showed that FeS and CaCO3 was the major mineralization product.
View Article and Find Full Text PDFAllicin, a small molecule that is responsible for the typical smell and most of the functions of garlic, possesses a broad spectrum of pharmacological activities and is considered to have therapeutic potential in many pathologic conditions. In the present study, we investigated the potential protective effect of allicin in an in vitro model of traumatic brain injury (TBI) using primary cultured rat cortical neurons. We found that allicin treatment significantly reduced mechanical trauma-induced lactate dehydrogenase (LDH) release and inhibited apoptotic neuronal death in a dose-dependent manner.
View Article and Find Full Text PDFBackground: Osthole, the main bioactive compounds isolated from the traditional Chinese medical herb broad Cnidium monnieri (L.) cusson, has been shown to exert spectrum of pharmacologic activities. The aim of this study was to investigate the potential neuroprotective effects of osthole against spinal cord ischemia-reperfusion injury in rats.
View Article and Find Full Text PDFThe effects of natural goethite (NGt) and synthetic goethite (SGt) on the release of methane in the anaerobic biochemical system consisted of dissimilatory iron-reducing bacteria (DIRB) and methane-producing bacteria (MPB) were investigated through batch tests with sodium acetate as the carbon source. To explore the effects and mechanisms of both mineral materials on the release of methane in the anaerobic decomposition process of organic matter in the presence of DIRB, the main gas components and total organic carbon (TOC) , total inorganic carbon (TIC), and Fe2+ in the aqueous phase of the experimental process were determined and XRD analyses were conducted for the solid-phase product. Moreover, the minerals were analyzed by specific surface area (BET), X-ray diffraction (XRD), X-ray fluorescence (XRF).
View Article and Find Full Text PDFMine tailings in Xiangsi Valley, Tongling, China, is a typical skarn-type tailing with high contents of carbonates. This study designed dynamic leaching experiments to investigate the efficiency of this tailing under the acid mine drainage treatment. During 80 d trial period, the physical and chemical properties of influents were fixed and the effluents were monitored.
View Article and Find Full Text PDFIn this study, with rape straw as carbon source, anaerobic batch experiments were executed to investigate the effect of Zn (II) on the activity of sulphate reducing bacteria (SRB) in the microbial treatment of simulative acid mine drainage (AMD). The results showed that during the 60 experimental days, when initial Zn2+ concentrations were in the range of 73.7 to 196.
View Article and Find Full Text PDFAcid mine drainage (AMD) and its natural neutralizing products in Wangjiatan iron mine were collected and analyzed by using spectroscopic and electron microanalytic methods. The results show that after natural neutralization of AMD by surface water of the stream, acidity and electric conductivity of AMD are both decreased. While for dissolved elements, no other element is obviously decreased except for Fe3+, SO4(2-), and Ca2+.
View Article and Find Full Text PDFThe preparation of 1-deoxy-d-xylulose 5-phosphate, the key intermediate of MEP biosynthetic pathway for terpenoids by using recombinant 1-deoxy-d-xylulose 5-phosphate synthase of Rhodobacter capsulatus was optimized. The simple one-pot synthesis coupling with a newly established ion-exchange purification process affords the target compound with more than 80% yield and high purity (>95%). The procedure can also be employed to synthesize isotope labeled 1-deoxy-d-xylulose 5-phosphate by using isotope labeled starting materials.
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