Higher dose of rivaroxaban for the treatment of venous thromboembolism in a 15-year-old Asian child with antithrombin deficiency: A case report and literature review.

Rationale: Deficiency in antithrombin (AT) can significantly increase the risk of venous thromboembolism (VTE). However, there is insufficient data on the efficacy and safety of anticoagulants in patients with AT deficiency, especially in children. In addition, Asian populations typically require a lower dose of rivaroxaban, and this may be even more pronounced in Asian children.

Two new compounds with anti-inflammatory activity from .

A new phenolic glycoside, chinenside A (), and a new megastigmane glycoside, chinenionside A (), together with twelve known compounds (), were isolated from the roots of . Their structures were deduced on the basis of extensive spectroscopic analyses and comparison with data reported in the literature. The anti-inflammatory activity in vitro of all 13 phenolic glycosides was evaluated against lipopolysaccharide-induced mouse macrophage RAW264.