Publications by authors named "Yue Yang Mo"
Article Synopsis
- Recent studies indicate that DNA methylation changes in various regions, not just promoter areas, during physiological processes and diseases.
- The current research found that black raspberries (BRBs) fed to mice reduced the development of colon and intestinal tumors through hypomethylation in various DNA regions.
- The hypomethylating effects of BRBs stem from a combination of their phytochemicals and gut bacterial metabolites, suggesting that similar benefits could be obtained from other fruits and vegetables.
The gut microbiota-the community of microorganisms in the gut-has been implicated in many physical and mental disorders in addition to intestinal diseases. Diets are the most studied and promising factors for altering it. Indeed, certain dietary interventions that increase fiber intake rapidly change levels of certain nutrients that can modify the composition of the microbiota, promoting richness and diversity.
View Article and Find Full Text PDFInnate immune cells in the tumor microenvironment have been proposed to control the transition from benign to malignant stages. In many cancers, increased infiltration of natural killer (NK) cells associates with good prognosis. Although the mechanisms that enable NK cells to restrain colorectal cancer (CRC) are unclear, the current study suggests the involvement of Smad4.
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