Effects of family relationship and social support on the mental health of Chinese postpartum women.

Background: Numerous studies suggest that interpersonal relationships and social support influence the development of postpartum depression and sleep quality for women. However, the effect of support from the husband or the mother-in-law has not been thoroughly validated. The current study examined the relative contribution of marital satisfaction, perceived caring of the mother-in-law, and social support on postpartum depression and sleep quality simultaneously in a path model.

A colorimetric biosensor for ultrasensitive detection of the gene based on a dual DNA-induced cascade hybridization reaction.

In this work, a simple and ultrasensitive colorimetric biosensor for detection of gene fragments (Leigh syndrome) has been developed based on a dual DNA-induced cascade hybridization reaction. Firstly, a biotin labeled capture probe was immobilized on a streptavidin labeled 96-well transparent plate surface. Then the target fragment and auxiliary probe S1 were added into the reaction system to form a "Y" structure with the capture probe.

Association between Maternal Serum 25(OH)-Vitamin D3 Levels in Late Pregnancy and Profiles of Newborn Amino Acid Concentrations.

Background: Vitamin D deficiency is common during pregnancy. 25(OH)-Vitamin D3 is the major vitamin D circulating form in human organism. However, the effects of 25(OH)-vitamin D3 deficiency in late pregnancy on the infant's amino acid metabolism has still not been studied.

[Prenatal diagnosis and genetic counseling in two pedigrees affected with infantile polycystic kidney disease due to PKHD1 gene mutations].

Objective: To detect potential mutations of the PKHD1 gene in two pedigrees affected with infantile polycystic kidney disease.

Methods: Clinical data and peripheral venous blood samples were collected from the probands and their parents as well as fetal amniotic fluid cells. Genome DNA was extracted from the peripheral blood samples and amniotic fluid cells.

Downregulation of microRNA-425-5p suppresses cervical cancer tumorigenesis by targeting AIFM1.

Although microRNA-425-5p (miR-425-5p) has been previously revealed to be upregulated in cervical cancer, the cellular function of miR-425-5p in cervical cancer remains unknown. The aim of the current study was to investigate the cellular function of miR-425-5p and its underlying mechanism in cervical cancer. Reverse transcription-quantitative polymerase chain reaction was used to measure miR-425-5p expression in several cervical cancer cell lines.

Factors influencing the quality of preconception healthcare in China: applying a preconceptional instrument to assess healthcare needs.

Background: Preconception care is defined as the promotion of the health and well-being of a woman and her partner before pregnancy. Improving preconception health can result in improved reproductive health outcomes. China has issued latest version official guideline for preconception care in 2011.

Perspectives of Chinese healthcare providers on medical abortion.

Objective: To evaluate Chinese healthcare providers' knowledge regarding medical abortion, to understand provider preferences for abortion methods, and to investigate the role of remuneration on providers' decision making.

Methods: Between November 2009 and May 2010, 658 abortion service providers from family-planning service centers and hospitals in Shenzhen and Henan, China, were surveyed via self-administered questionnaires.

Results: The knowledge score (out of a maximum of 32) regarding medical abortion was 16-20 for 60.