Concurrently Boosting Activity and Stability of Oxygen Reduction Reaction Catalysts via Judiciously Crafting Fe-Mn Dual Atoms for Fuel Cells.

The ability to unlock the interplay between the activity and stability of oxygen reduction reaction (ORR) represents an important endeavor toward creating robust ORR catalysts for efficient fuel cells. Herein, we report an effective strategy to concurrent enhance the activity and stability of ORR catalysts via constructing atomically dispersed Fe-Mn dual-metal sites on N-doped carbon (denoted (FeMn-DA)-N-C) for both anion-exchange membrane fuel cells (AEMFC) and proton exchange membrane fuel cells (PEMFC). The (FeMn-DA)-N-C catalysts possess ample dual-metal atoms consisting of adjacent Fe-N and Mn-N sites on the carbon surface, yielded via a facile doping-adsorption-pyrolysis route.

Arbuscular Mycorrhizal Fungi Selectively Promoted the Growth of Three Ecological Restoration Plants.

Arbuscular mycorrhizal inoculation can promote plant growth, but specific research on the difference in the symbiosis effect of arbuscular mycorrhizal fungi and plant combination is not yet in-depth. Therefore, this study selected L., , and Schreb.

Polyacrylate modified Cu electrode for selective electrochemical CO reduction towards multicarbon products.

Highly selective production of value-added multicarbon (C) products via electrochemical CO reduction reaction (eCORR) on polycrystalline copper (Cu) remains challenging. Herein, the facile surface modification using poly (α-ethyl cyanoacrylate) (PECA) is presented to greatly enhance the C selectivity for eCORR over polycrystalline Cu, with Faradaic efficiency (FE) towards C products increased from 30.1% for the Cu electrode to 72.

Defect Engineering Simultaneously Regulating Exciton Dissociation in Carbon Nitride and Local Electron Density in Pt Single Atoms Toward Highly Efficient Photocatalytic Hydrogen Production.

The high exciton binding energy (E) and sluggish surface reaction kinetics have severely limited the photocatalytic hydrogen production activity of carbon nitride (CN). Herein, a hybrid system consisting of nitrogen defects and Pt single atoms is constructed through a facile self-assembly and photodeposition strategy. Due to the acceleration of exciton dissociation and regulation of local electron density of Pt single atoms along with the introduction of nitrogen defects, the optimized Pt-MCT-3 exhibits a hydrogen production rate of 172.

An Interface-cascading Silicon Photoanode with Strengthened Built-in Electric Field and Enriched Surface Oxygen Vacancies for Efficient Photoelectrochemical Water Splitting.

To promote interfacial charge transfer process and accelerate surface water oxidation reaction kinetics for photoelectrochemical (PEC) water splitting over n-type Silicon (n-Si) based photoanodes, herein, starting with surface stabilized n-Si/CoO , a NiO /NiFeOOH composite overlayer was coated by atomic layer deposition and spray coating to fabricate the multilayer structured n-Si/CoO /NiO /NiFeOOH photoanode. Encouragingly, the obtained n-Si/CoO /NiO /NiFeOOH photoanode exhibits much increased PEC activity for water splitting, with onset potential cathodically shifted to ~0.96 V vs.

Primary mucinous adenocarcinoma of the urethra: A clinicopathological analysis of 35 cases.

Aim: Primary mucinous adenocarcinoma of the urethra represents an extremely rare entity. We sought to characterise further these tumours' clinicopathological, immunohistochemical and molecular features.

Methods And Results: Thirty-five cases were identified, occurring in 18 males and 17 females.

Surface Adsorbed Hydroxyl: A Double-Edged Sword in Electrochemical CO Reduction over Oxide-Derived Copper.

Oxide-derived Cu (OD-Cu) featured with surface located sub-20 nm nanoparticles (NPs) created via surface structure reconstruction was developed for electrochemical CO reduction (ECO RR). With surface adsorbed hydroxyls (OH ) identified during ECO RR, it is realized that OH , sterically confined and adsorbed at OD-Cu by surface located sub-20 nm NPs, should be determinative to the multi-carbon (C ) product selectivity. In situ spectral investigations and theoretical calculations reveal that OH favors the adsorption of low-frequency *CO with weak C≡O bonds and strengthens the *CO binding at OD-Cu surface, promoting *CO dimerization and then selective C production.

Decrypting the Controlled Product Selectivity over Ag-Cu Bimetallic Surface Alloys for Electrochemical CO Reduction.

Electrochemical CO reduction reaction (ECO RR) with controlled product selectivity is realized on Ag-Cu bimetallic surface alloys, with high selectivity towards C2 hydrocarbons/alcohols (≈60 % faradaic efficiency, FE), C1 hydrocarbons/alcohols (≈41 % FE) and CO (≈74 % FE) achieved by tuning surface compositions and applied potentials. In situ spectral investigations and theoretical calculations reveal that surface-composition-dependent d-band center could tune *CO binding strengths, regulating the *CO subsequent reaction pathways and then the product selectivity. Further adjusting the applied potentials will alter the energy of participated electrons, which leads to controlled ECO RR selectivity towards desired products.

LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer.

The major histocompatibility complex class I (MHC-I) transactivator, nucleotide binding oligomerization domain-like receptor family caspase recruitment domain containing 5 (NLRC5), serves as a target for immune evasion in many cancers, including endometrial cancer (EC). An inhibition of autophagy can contribute to immunotherapy by assisting the MHC-I-mediated antigen presentation in cancer. However, the underlying mechanism for autophagy-regulated MHC-I in EC remains unclear.

Chrysin induces autophagy through the inactivation of the ROS‑mediated Akt/mTOR signaling pathway in endometrial cancer.

Endometrial cancer (EC) is widely known as an aggressive malignancy. Due to the limited therapeutic options and poor prognosis of patients with advanced‑stage EC, there is a need to identify effective alternative treatments. Chrysin is a naturally active flavonoid (5,7‑dihydroxyflavone), which has been demonstrated to exert anticancer effects and may present a novel strategy for EC treatment.

Circular RNAs: Novel biomarkers for cervical, ovarian and endometrial cancer (Review).

Cervical, ovarian and endometrial cancer are the three most common types of malignant tumor and the leading causes of cancer‑associated death in women. Tumor debulking surgery followed by platinum and paclitaxel chemotherapy is the current treatment regime of choice. However, as a result of late diagnosis and chemoresistance, the survival rates of patients with advanced gynecological cancers remains unsatisfactory.

Potential relationship between Sirt3 and autophagy in ovarian cancer.

Sirtuin 3 (Sirt3) is an important member of the sirtuin protein family. It is a deacetylase that was previously reported to modulate the level of reactive oxygen species (ROS) production and limit the extent of oxidative damage in cellular components. As an important member of the class III type of histone deacetylases, Sirt3 has also been documented to mediate nuclear gene expression, metabolic control, neuroprotection, cell cycle and proliferation.

Ionic liquid assisted electrochemical coating zinc nanoparticles on carbon cloth as lithium dendrite suppressing host.

The application of lithium metal anode with high specific capacity and energy density is limited by the volume expansion and pulverization caused by dendrite growth during cycle process. We propose a composite lithium anode by immersing molten lithium on the flexible three-dimensional (3D) carbon cloth scaffold with the zinc nanoparticles. The lithiophilic zinc nanoparticles layer of framework is synthesized by fast and easy electrochemical deposition from ionic liquid avoiding high temperature, high pressure and toxic reagent.

NLRC5 promotes cell migration and invasion by activating the PI3K/AKT signaling pathway in endometrial cancer.

Objective: NOD-like receptor family caspase recruitment domain family domain-containing 5 (NLRC5) is involved in the development of cancer. Our objective was to explore the role of NLRC5 in the progression of endometrial cancer (EC).

Methods: The roles of NLRC5 in migration and invasion of AN3CA EC cells were examined by cell wound-healing assay, Transwell migration, and invasion analysis.

An Overview and Future Perspectives of Rechargeable Zinc Batteries.

Aqueous rechargeable zinc-based batteries have sparked a lot of enthusiasm in the energy storage field recently due to their inherent safety, low cost, and environmental friendliness. Although remarkable progress has been made in the exploration of performance so far, there are still many challenges such as low working voltage and dissolution of electrode materials at the material and system level. Herein, the central tenet is to establish a systematic summary for the construction and mechanism of different aqueous zinc-based batteries.