Publications by authors named "Yuchong Hu"

Article Synopsis
  • The study aimed to validate the PAX1 and JAM3 methylation test as a better tool for detecting severe cervical issues (CIN3 +) in patients who tested positive for HPV but were not infected with the high-risk types 16 or 18.
  • Results from 1851 participants showed that the PAX1/JAM3 test had higher specificity and successfully detected all cases of cancer, significantly reducing the number of unnecessary referrals for further examination compared to traditional liquid-based cytology.
  • Overall, the PAX1/JAM3 test outperformed the liquid-based cytology method in identifying CIN3 +  cases, offering a more efficient approach without losing sensitivity in diagnosis.
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Aims: To examine the factors influencing compassion fatigue and compassion satisfaction in obstetrics and gynaecology nurses and to explore the combined results of multiple factors.

Design: An online cross-sectional study was conducted.

Review Methods: Data were collected from 311 nurses using a convenience sampling method from January to February 2022.

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The acquisition of cancer stem-like properties is believed to be responsible for cancer metastasis and therapeutic resistance in cervical cancer (CC). CC tissues display a high expression level of hexokinase 2 (HK2), which is critical for the proliferation and migration of CC cells. However, little is known about the functional role of HK2 in the maintenance of cancer stem cell-like ability and cisplatin resistance of CC cells.

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Cervical cancer is one of the most common gynecological cancers. Cisplatin resistance remains a major hurdle in the successful treatment of cervical cancer. Aberrant expression of long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are implicated in cisplatin resistance.

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Real data often appear in the form of multiple incomplete views. Incomplete multiview clustering is an effective method to integrate these incomplete views. Previous methods only learn the consistent information between different views and ignore the unique information of each view, which limits their clustering performance and generalizations.

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Sanwei-Tanxiang powder (SWTX), a traditional Mongolian and Tibetan medicine containing a cocktail of active molecules, relieves angina pectoris and improves recovery in patients with coronary heart disease (CHD). The pharmacological effect of SWTX on CHD was analyzed at a systemic point of view in our previous studies. The bioinformatics prediction showed that the PI3K/Akt/FoxO3a pathway was one of important pathways of SWTX on treatment of coronary heart disease.

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GuangZao and RouDouKou ( and , FCN) are one of the most common herb pairs in traditional Mongolian medicine for the treatment of coronary heart disease (CHD). However, evidence for the protective effect of FCN is limited, and its underlying mechanism of action remains unclear. The present study employed a network pharmacology approach to identify the potentially active ingredients and synergistic effects of the herb pair FCN as traditional Mongolian medicine.

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