Relationship between macular microvasculature and visual function in idiopathic macular epiretinal membrane by using OCT angiography and multifocal electroretinogram.

Purpose: To investigate the relationship between microvasculature and visual function in idiopathic epiretinal membrane (iERM).

Methods: This retrospective study included 30 iERM eyes. Macular microvasculature was evaluated by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).

A novel and facile oxygen-activated time-temperature indicator with wide temperature monitoring range and good stability based on the laccase-like nanozyme.

Background: Time-Temperature Indicator (TTI) is an indicator device for real-time monitoring of the thermal history of the product. Due to the enzymatic reactions are affected by both time and temperature, enzymatic TTIs have been extensively studied and developed in recent years. However, enzymatic TTIs contain biologically active molecules (enzymes), which require high storage and use conditions.

Polystyrene nanoplastics enhance thrombosis through adsorption of plasma proteins.

Plastic products offer remarkable convenience for modern life. However, growing concerns are emerging regarding the potential health hazards posed by nanoplastics, which formed as plastics break down. Currently, the biological effects and mechanisms induced by nanoplastics are largely underexplored.

Comparative analysis of dental implant placement accuracy: Semi-active robotic versus free-hand techniques: A randomized controlled clinical trial.

Background: Robot-assisted implant surgery has emerged as a novel digital technology, and the accuracy need further assessment.

Purpose: This study aimed to compare the accuracy of single dental implant placement between a novel semi-active robot-assisted implant surgery (RAIS) method and the conventional free-hand implant surgery (FHIS) method through a multicenter, randomized controlled clinical trial.

Materials And Methods: Patients requiring single dental implant placement were recruited and randomized into RAIS and FHIS group.

Structural and functional abnormalities across clinical stages of psychosis: A multimodal neuroimaging investigation.

Background: Structural and functional neurobiological abnormalities have been observed in schizophrenia. Previous studies have concentrated on specific illness stages, obscuring relationships between functional/structural changes and disorder progression. The present study aimed to quantify structural and functional abnormalities across different clinical stages using functional near-infrared spectroscopy (fNIRS) and structural magnetic resonance imaging (sMRI).

The Asian rock-dwelling antlions Navás, 1915 and Navás, 1914 (Neuroptera: Myrmeleontidae): new advancements in systematics, biogeography and life history.

The antlion genera Gatzara and Nepsalus (Myrmeleontidae: Dendroleontinae) inhabit mountain forests and are characterised by camouflaging larvae. Both genera remain poorly known despite recent findings on systematics and distribution. We report the discovery of new specimens and the previously unknown larvae of the rare species Gatzara jubilaea Navás, 1915, Nepsalus insolitus (Walker, 1860) and N.

Taxonomic notes on two antlion genera Holzezus Krivokhatsky, 1992 and Subgulina Krivokhatsky, 1996 (Neuroptera: Myrmeleontidae: Myrmecaelurini) from China.

A little-known antlion genus, i.e., Holzezus Krivokhatsky, 1992, with its type species H.

Early energy performance analysis of smart buildings by consolidated artificial neural network paradigms.

The assessment of energy performance in smart buildings has emerged as a prominent area of research driven by the increasing energy consumption trends worldwide. Analyzing the attributes of buildings using optimized machine learning models has been a highly effective approach for estimating the cooling load (C) and heating load (H) of the buildings. In this study, an artificial neural network (ANN) is used as the basic predictor that undergoes optimization using five metaheuristic algorithms, namely coati optimization algorithm (COA), gazelle optimization algorithm (GOA), incomprehensible but intelligible-in-time logics (IbIL), osprey optimization algorithm (OOA), and sooty tern optimization algorithm (STOA) to predict the C and H of a residential building.

Intracellular Protein Adsorption Behavior and Biological Effects of Polystyrene Nanoplastics in THP-1 Cells.

Micro(nano)plastics (MNPs) are emerging pollutants that can adsorb pollutants in the environment and biological molecules and ultimately affect human health. However, the aspects of adsorption of intracellular proteins onto MNPs and its biological effects in cells have not been investigated to date. The present study revealed that 100 nm polystyrene nanoplastics (NPs) could be internalized by THP-1 cells and specifically adsorbed intracellular proteins.

A new species of the alderfly genus Sialis Latreille, 1802 (Megaloptera: Sialidae) from southeastern China.

Here we describe a new species of the alderfly genus Sialis Latreille, 1802 from southeastern China, namely S. kouwenkaii sp. nov.

Transcriptomic Analysis of THP-1 Cells Exposed by Monosodium Urate Reveals Key Genes Involved in Gout.

Background: Gout is a common inflammatory arthritis, which is mainly caused by the deposition of monosodium urate (MSU) in tissues. Transcriptomics was used to explore the pathogenesis and treatment of gout in our work.

Objective: The objective of the study was to analyze and validate potential therapeutic targets and biomarkers in THP-1 cells that were exposed to MSU.

Three-dimensional evaluation of the association between tongue position and upper airway morphology in adults: A cross-sectional study.

Objective: This study aimed to evaluate the association between low tongue position (LTP) and the volume and dimensions of the nasopharyngeal, retropalatal, retroglossal, and hypopharyngeal segments of the upper airway.

Methods: A total of 194 subjects, including 91 males and 103 females were divided into a resting tongue position (RTP) group and a LTP group according to their tongue position. Subjects in the LTP group were divided into four subgroups (Q1, Q2, Q3, and Q4) according to the intraoral space volume.

Cyclin-G-associated kinase GAK/dAux regulates autophagy initiation via ULK1/Atg1 in glia.

Autophagy is a major means for the elimination of protein inclusions in neurons in neurodegenerative diseases such as Parkinson's disease (PD). Yet, the mechanism of autophagy in the other brain cell type, glia, is less well characterized and remains largely unknown. Here, we present evidence that the PD risk factor, Cyclin-G-associated kinase (GAK)/ homolog Auxilin (dAux), is a component in glial autophagy.

HPV18 E6 inhibits α-ketoglutarate-induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway.

Oncogene E6 plays a critical role in the development and progression of esophageal cancer caused by human papillomavirus (HPV) infection. Alpha-ketoglutarate (AKG) is a key metabolite in the tricarboxylic acid cycle and has been widely used as a dietary and anti-ageing supplement. In this study, we found that treating esophageal squamous carcinoma cells with a high dose of AKG can induce cell pyroptosis.

A revision of the Oriental antlion genera Indoleon Banks, 1913, Indophanes Banks, 1940 and Yunleon Yang, 1986 (Neuroptera: Myrmeleontidae: Nemoleontinae).

This paper deals with three Oriental genera of the antlion subfamily Nemoleontinae. The validity of two junior synonyms of Indoleon Banks, 1913, i.e.

Taxonomic notes on the antlion tribe Palparini Banks (Neuroptera: Myrmeleontidae) from Pakistan.

The antlion tribe Palparini Banks, 1911 (Myrmeleontidae: Ascalaphinae) currently comprises five genera and seven species in Pakistan. The taxonomic status of three genera, namely Indopalpares Insom & Carfi, 1988, Palpares Rambur, 1842, and Parapalpares Insom & Carfi, 1988, are revised herein. Indopalpares pardus (Rambur, 1842), Palpares zebratus Rambur, 1842, and Parapalpares solidus (Gerstaecker, 1894) are redescribed based on the material from the northern areas of Pakistan.

Transcriptomic analysis of the effects of the HPV18 E6E7 gene on the cell death mode in esophageal squamous cell carcinoma.

Human papillomavirus (HPV) infection is one of the main causes of esophageal carcinoma (ESCA), and its carcinogenic mechanisms in ESCA require further investigation. E6 and E7 are HPV oncogenes, and their genomic integration is a crucial reason for the transformation of host cells into cancer cells. In order to reveal the role of oncogenes E6 and E7 in ESCA cells, the RNA-Seq raw data for HPV18-positive and -negative esophageal squamous cell carcinoma (ESCC) samples derived from the NCBI BioProject database were analyzed, and the differentially expressed genes were identified.

Ultrastrong coupling in Super Yellow polymer microcavities and development of highly efficient polariton light-emitting diodes and light-emitting transistors.

We present detailed studies on exciton-photon coupling and polariton emission based on a poly(1,4-phenylenevinylene) copolymer, Super Yellow (SY), in a series of optical microcavities and optoelectronic devices, including light-emitting diode (LED) and light-emitting transistor (LET). We show that sufficiently thick SY microcavities can generate ultrastrong coupling with Rabi splitting energies exceeding 1 eV and exhibit spectrally narrow, nearly angle-independent photoluminescence following lower polariton (LP) mode dispersion. When the microcavity is designed with matched LP low-energy state and exciton emission peak for radiative pumping, the conversion efficiency from exciton to polariton emission can reach up to 80%.

Swin Unet3D: a three-dimensional medical image segmentation network combining vision transformer and convolution.

Background: Semantic segmentation of brain tumors plays a critical role in clinical treatment, especially for three-dimensional (3D) magnetic resonance imaging, which is often used in clinical practice. Automatic segmentation of the 3D structure of brain tumors can quickly help physicians understand the properties of tumors, such as the shape and size, thus improving the efficiency of preoperative planning and the odds of successful surgery. In past decades, 3D convolutional neural networks (CNNs) have dominated automatic segmentation methods for 3D medical images, and these network structures have achieved good results.

SbNAC9 Improves Drought Tolerance by Enhancing Scavenging Ability of Reactive Oxygen Species and Activating Stress-Responsive Genes of Sorghum.

Drought stress severely threatens the yield of cereal crops. Therefore, understanding the molecular mechanism of drought stress response of plants is crucial for developing drought-tolerant cultivars. NAC transcription factors (TFs) play important roles in abiotic stress of plants, but the functions of NAC TFs in sorghum are largely unknown.

Phylogenetic implications of the complete mitochondrial genome of (Westwood, 1847) and first record of the genus Westwood, 1847 from China (Neuroptera, Myrmeleontidae, Ascalaphinae).

Background: The genus Westwood, 1847, which is endemic to the Oriental Region and contains only five species, has been recorded in India and Pakistan, but not in China. The genus was not sampled in any previous study on the phylogeny of Neuroptera and its affinity within Ascalaphinae is unclear.

New Information: The owlfly species (Westwood, 1847) is firstly recorded from China, based on a female specimen collected from Yunnan Province, which represents the first record of the genus from China.

Ethylene-responsive SbWRKY50 suppresses leaf senescence by inhibition of chlorophyll degradation in sorghum.

The onset of leaf de-greening and senescence is governed by a complex regulatory network including environmental cues and internal factors such as transcription factors (TFs) and phytohormones, in which ethylene (ET) is one key inducer. However, the detailed mechanism of ET signalling for senescence regulation is still largely unknown. Here, we found that the WRKY TF SbWRKY50 from Sorghum bicolor L.

Status and clinical influencing factors of involuntary admission in chinese patients with schizophrenia.

Background: Though controversial for its various disadvantages, involuntary admission (IA) is necessary in providing mental health care for patients suffering from schizophrenia in China. This article examines the IA rate in a representative sample, and under which circumstances are these patients more likely to be admitted involuntarily.

Methods: Adult patients consecutively admitted to two typical hospitals in Shanghai between 2013 and 2014 with a diagnosis of ICD-10 schizophrenia were included.

An imConvNet-based deep learning model for Chinese medical named entity recognition.

Background: With the development of current medical technology, information management becomes perfect in the medical field. Medical big data analysis is based on a large amount of medical and health data stored in the electronic medical system, such as electronic medical records and medical reports. How to fully exploit the resources of information included in these medical data has always been the subject of research by many scholars.